Table 3

OR of RA together with 95% CI among workers classified as ever exposed to asbestos or silica in different censuses compared with workers classified as never exposed (n=126 534)

All RA casesSeropositive RASeronegative RA
Cases/controlsMedian intensity for asbestos (fibre/cm3) and silica (mg/m3)Median years since last occupation classified as exposedCrude OR
(95 % CI)*
Adjusted OR
(95 % CI)†
Crude OR
(95 % CI)*
Adjusted OR
(95 % CI)†
Crude OR
(95 % CI)*
Adjusted OR
(95 % CI)†
Asbestos
Men
 Unexposed workers2151/24 0331.01.01.01.01.01.0
 Exposed from 196084/7810.10401.2 (1.0 to 1.5)1.0 (0.8 to 1.3)1.2 (0.9 to 1.6)1.0 (0.7 to 1.4)1.2 (0.8 to 1.7)1.1 (0.7 to 1.6)
 Exposed from 1970306/21480.11351.7 (1.5 to 1.9)1.3 (1.1 to 1.5)1.7 (1.5 to 2.0)1.3 (1.1 to 1.6)1.5 (1.2 to 1.9)1.3 (1.0 to 1.7)
 Exposed from 197583/7110.17321.3 (1.1 to 1.7)0.9 (0.7 to 1.2)1.5 (1.1 to 1.9)1.1 (0.8 to 1.5)1.0 (0.7 to 1.6)0.7 (0.4 to 1.1)
 Exposed from 19801/100.0227
 Exposed from 19900/50.0420
Silica
Men
 Unexposed workers2956/32 3611.01.01.01.01.01.0
 Exposed from 1960151/10180.1035.01.6 (1.4 to 2.0)1.4 (1.1 to 1.7)1.9 (1.6 to 2.4)1.6 (1.3 to 2.1)1.2 (0.9 to 1.6)1.0 (0.7 to 1.4)
 Exposed from 1970233/14870.0826.01.7 (1.5 to 2.0)1.4 (1.2 to 1.7)1.9 (1.6 to 2.2)1.5 (1.2 to 1.8)1.5 (1.2 to 2.0)1.3 (1.0 to 1.7)
 Exposed from 1975102/7690.0928.01.5 (1.2 to 1.8)1.2 (0.9 to 1.5)1.5 (1.2 to 2.0)1.2 (0.9 to 1.6)1.3 (0.9 to 1.9)1.1 (0.8 to 1.6)
 Exposed from 198085/7290.0726.01.3 (1.0 to 1.6)1.1 (0.9 to 1.5)1.2 (0.9 to 1.6)1.1 (0.8 to 1.4)1.4 (1.0 to 2.0)1.3 (0.9 to 1.9)
 Exposed from 199083/6110.0517.51.5 (1.2 to 1.8)1.3 (1.0 to 1.7)1.4 (1.0 to 1.8)1.2 (0.9 to 1.6)1.7 (1.1 to 2.4)1.6 (1.1 to 2.4)
Women
 Unexposed workers7558/77 3701.01.01.01.01.01.0
 Exposed from 196012/880.1046.01.4 (0.8 to 2.6)1.2 (0.7 to 2.3)1.9 (1.0 to 3.5)1.6 (0.8 to 3.1)
 Exposed from 19709/720.1835.01.3 (0.6 to 2.6)1.1 (0.5 to 2.3)1.4 (0.7 to 3.1)1.1 (0.5 to 2.6)
 Exposed from 197516/1100.1831.01.5 (0.9 to 2.5)1.3 (0.7 to 2.2)1.8 (1.0 to 3.2)1.5 (0.8 to 2.7)
 Exposed from 198016/1520.0527.01.1 (0.6 to 1.8)0.9 (0.5 to 1.6)1.2 (0.7 to 2.2)1.0 (0.5 to 1.9)
 Exposed from 19907/740.0517.01.0 (0.4 to 2.1)0.8 (0.4 to 1.8)0.9 (0.4 to 2.3)0.8 (0.3 to 2.0)
  • *Adjusted for county, age and index year.

  • †Adjusted for county, age, index year, pack-years of smoking and alcohol consumption. Asbestos and silica were adjusted for each other.

  • RA, rheumatoid arthritis.