Table 2

OR of RA together with 95% CI among workers classified as ever exposed to asbestos or silica compared with workers classified as never exposed (n=1 26 534)

All RA casesSeropositive RASeronegative RA
Exposed cases/controlsUnexposed cases/controlsMedian intensity for asbestos (fibre/cm3) and silica (mg/m3)Median years since last occupation classified as exposedCrude OR
(95 % CI)*
Adjusted OR
(95 % CI)
Crude OR
(95 % CI)*
Adjusted OR
(95 % CI)
Crude OR
(95 % CI)*
Adjusted OR
(95 % CI)†
Asbestos
 Men603/46242151/24 0330.10351.5 (1.3 to 1.6)1.2 (1.0 to 1.3)1.6 (1.4 to 1.8)1.2 (1.0 to 1.4)1.4 (1.2 to 1.6)1.2 (1.0 to 1.5)
 Women17/1397359/75 5260.02321.3 (0.8 to 2.1)1.0 (0.6 to 1.7)1.5 (0.9 to 2.6)1.1 (0.6 to 2.0)
 Men and women‡620/47639510/99 5590.10351.5 (1.3 to 1.6)1.1 (1.0 to 1.2)1.5 (1.4 to 1.7)1.1 (0.9 to 1.2)1.3 (1.1 to 1.6)1.2 (1.0 to 1.4)
Silica
 Men678/47032956/32 3610.08251.6 (1.4 to 1.7)1.3 (1.2 to 1.5)1.7 (1.5 to 1.9)1.4 (1.2 to 1.6)1.4 (1.2 to 1.6)1.3 (1.0 to 1.5)
 Women64/5327558/77 3700.10291.2 (0.9 to 1.6)1.1 (0.8 to 1.5)1.4 (1.1 to 1.9)1.2 (0.8 to 1.7)0.8 (0.4 to 1.4)0.8 (0.4 to 1.5)
 Men and women‡742/523510 514/109 7310.08261.5 (1.4 to 1.7)1.3 (1.2 to 1.5)1.6 (1.5 to 1.8)1.4 (1.2 to 1.5)1.3 (1.1 to 1.5)1.2 (1.0 to 1.4)
  • *Adjusted for county, age and index year.

  • †Adjusted for county, age, index year, pack-years of smoking and alcohol consumption. Asbestos and silica were adjusted for each other.

  • ‡ Additionally adjusted for sex.

  • RA, rheumatoid arthritis.