Table 1

Description of 55 articles on big data in RMDs, and 55 articles for comparison outside RMDs

RMDsOther medical fields
Year of publication, mean (SD) (range)2014 (4.6) (1992–2018)2018 (0.4) (2018–2019)
Year of publication: last 5 years, N (%)40 (72)55 (100)
Impact factor, mean (SD) (range)3.8 (4.0) (0.35–23.3)5.56 (9.8) (0.56–47.7)
Geographic origin of the first author, N (%)
 North America N=15 (34%)21 (38)17 (31)
 Europe18 (33)18 (33)
 Asia15 (27)19 (34)
 Australia0 (0)1 (2)
 South America1 (2)0 (0)
 Africa0 (0)0 (0)
Clear definition of big data, N (%)2 (4)7 (13)
N data analysed
 Units of observation, mean (SD) (range)1 142 000 (3 990 000) (5–25 000 000)5 298 000 (23 909 000) (40–140 000 000)
 Data points, mean (SD) (range)746 000 000 (1 660 000 000) (2000–5 000 000 000)9 149 000 000 (39 000 000 000) (100 000–200 000 000 000)
Clinical data sources, N (%)26 (47)17 (31)
 Registries/cohorts, N (%)14 (25)10 (18)
 EHR11 (20)3 (6)
 Claims databases1 (2)0 (0)
 Trials0 (0)0 (0)
 PGHD (sensors, etc)0 (0)4 (7)
 Other0 (0)0 (0)
Biological data, N (%)8 (15)17 (31)
 –omics8 (15)17 (31)
 Other0 (0)0 (0)
Imaging, N (%)16 (29)16 (29)
Other data sources5 (9)5 (9)
Text-mining from publications5 (9)5 (9)
Other 0 (0) 0 (0)
  • EHR, Electronic Health Record; PGHD, Patient Generated Health Data.