Table 1

Baseline characteristics of the population

CharacteristicsTotal population
(N=203)
Second TNFi
(n=96)
Other biologic (n=107)P value for comparison of second TNFi versus other biologic
Age (median, IQR), years56.8 (47.8–65.3)56.0 (45.4–64.3)57.3 (50.2–67.2)0.074*
Women (%)81.883.380.40.586†
RF and/or anti-CCP (%)89.986.393.20.108†
DAS28 ESR (median, IQR)5.0 (4.2–5.8)5.0 (4.1–5.6)5.0 (4.4–5.9)0.196‡
CRP (median, in mg/L)8.59.07.70.850‡
Corticosteroid (%)49.847.951.40.620†
Methotrexate (%)82.783.581.90.786†
BMI (median, IQR) kg/m224.5 (21.3–28.7)24.5 (21.3–28)24.5 (21.5–29)0.766‡
Hypertension (%)52.84956.10.462†
Diabetes (%)1714.119.30.493†
Smokers (%)3434.733.30.883†
Dyslipidaemia (%)34.928.640.40.205†
  • Statistical analysis.

  • *Student’s t-test.

  • †χ2 test.

  • ‡Wilcoxon test.

  • BMI, body mass index; CCP, cyclic citrullinated peptide; CRP, C reactive protein; DAS28, Disease Activity Score in 28 joints; ESR, erythrocyte sedimentation rate;RF, rheumatoid factor; TNFi, tumour necrosis factor inhibitor.