Table 2

(A): Health utilisation, and (B) health costs per patient 12 months before and after switch, unadjusted and adjusted (=predicted)* n=1620 patients

(A) Total health utilisation per patientUnadjusted number, mean (SD)Adjusted number, mean (95% CI)*
PreswitchPost-switchPreswitchPostswitch
OutpatientNumber of outpatient visits12.30 (9.40)13.31 (9.75)9.42 (7.91 to 11.22)11.09 (9.34 to 13.16)
Inpatient servicesNumber of inpatient admissions0.25 (0.64)0.11 (0.40)0.15 (0.03 to 0.67)0.06 (0.01 to 0.69)
Number of days in hospital1.19 (5.26)0.49 (2.73)0.66 (0.06 to 7.25)0.20 (0.004 to 10.47)
Medication†Pain medication171 (254)170 (250)168 (88 to 320)165 (86 to 315)
Other medication937 (1119)955 (1135)659 (355 to 1223)678 (364 to 1262)
Total1108 (1225)1124 (1241)832 (447 to 1549)848 (455 to 1584)
(B) Total health costs per patientUnadjusted average cost, mean (SD)Adjusted average cost, mean (95% CI)*
Preswitch, €Postswitch, €Preswitch, €Postswitch, €
Inpatient servicesDiseases of the musculoskeletal system and connective tissue315 (1645)306 (2330)122 (58 to 258)385 (144 to 1030)
Other diseases1014 (4326)1121 (4607)491 (268 to 902)297 (150 to 587)
Total1330 (4720)1428 (5501)660 (355 to1227)500 (255to 977)
Outpatient servicesDiseases of the musculoskeletal system and connective tissue4445 (6898)4700 (7381)4051 (2171 to 7559)4040 (2150 to 7589)
Other diseases860 (2623)1069 (3498)368 (197 to 688)484 (253 to 928)
Total5305 (7369)5769 (8107)4436 (2529 to7779)4593 (2618to 8059)
Primary sector†General practitioner201 (208)208 (218)171 (93 to 314)174 (95 to 318)
Other practicing specialist105 (229)103 (211)98 (53 to 180)89 (48 to 164)
Physiotherapist, chiropractor, foot specialist397 (807)384 (801)423 (222 to 807)388 (200 to 751)
Other75 (112)70 (97)66 (35 to 124)63 (33 to 118)
Total778 (936)765 (921)756 (408 to1404)709 (381to 1321)
Medication‡Pain medication75 (239)74 (231)63 (33 to 119)62 (32 to 118)
Other medication391 (638)372 (595)255 (136 to 478)250 (134 to 466)
Total466 (721)446 (682)321 (172 to601)312 (167to 584)
Total costs7880 (9427)8408 (10489)6176 (3685 to10353)6264 (3741to 10491)
  • *Predicted costs are for female, 55 years old, not dead in the postswitch period, not withdrawn SB4 within 0–180 days, previous duration of ETA treatment >5 years and with no previous comorbidities.

  • †For primary sector, no specific data are available for health utilisation thus only costs are shown.

  • ‡Defined daily dose of medication total costs.