Table 3

(A) Changes in health utilisation, and (B) changes in costs per patient 12 months before and after switch including adjusting variables*

		After*
		Exp (estimate), 95% CI	P value
(A) Changes in health utilisation per patient
Inpatient services	Number of inpatient admissions	0.45 (0.37 to0.54)	<0.0001
Inpatient services	Number of days in hospital	0.36 (0.25 to0.51)	<0.0001
Outpatient	Number of outpatient visits	1.08 (1.05 to1.11)	<0.0001
Medication†	Pain medication, DDD	0.99 (0.96 to 1.03)	0.702
	Other medication	1.03 (1.00 to 1.05)	0.051
	Total	1.02 (1.00 to 1.04)	0.100
(B) Changes in health costs per patient
Inpatient services	Diseases of the musculoskeletal system and connective tissue	0.70 (0.44 to 1.10)	0.119
	Other diseases	0.81 (0.62 to 1.05)	0.114
	Total	0.82 (0.65 to 1.04)	0.100
Outpatient services	Diseases of the musculoskeletal system and connective tissue	1.05 (1.00 to 1.10)	0.057
	Other diseases	1.24 (1.09 to1.41)	0.001
	Total	1.07 (1.03 to1.12)	0.001
Primary sector	General practitioner	1.03 (0.99 to 1.08)	0.130
	Other practicing specialist	0.97 (0.85 to 1.10)	0.603
	Physiotherapist, chiropractor, foot specialist	0.97 (0.92 to 1.02)	0.258
	Other	0.94 (0.88 to 1.02)	0.140
	Total	0.99 (0.95 to 1.02)	0.426
Medication	Pain medication	0.98 (0.93 to 1.03)	0.331
	Other medication	0.95 (0.91 to 1.00)	0.061
	Total	0.95 (0.92 to0.99)	0.019
Total costs		1.04 (0.99 to 1.09)	0.138

Statistically significant results are marked with bold types.
*Adjusted for gender, age, dead in post period, duration of ETA before index date, stopped SB4 treatment within 180 days and comorbidities (WHO chapters) 12–24 months before index date.
†Defined daily dose of medication total costs (DDD).