Table 2

Baseline features of the study cohorts

HCs (n=57)PsO (n=57)PsOAr (n=61)P value
PsOAr vs PsO vs HCs
P value
PsO vs HCs
P value
PsOAr vs HCs
P value
PsOAr vs PsO
Baseline data
 Age, mean (±SD)47.91 (±13.03)50.65 (±16.62)50.49 (±12.27)0.44n.a.n.a.n.a.
 Female, n (%)39 (69.64%)28 (49.12%)34 (55.74%)0.08n.a.n.a.n.a.
 Smoking, n (%)8 (14.55%)17 (29.82%)5 (8.2%)0.020.140.150.008
 BMI, mean (±SD)23 (±3.67)25 (±3.95)26 (±4.8)<0.0010.0020.0010.96
 Family history of PsA, n (%)1 (1.75%)9 (16.07%)7 (11.48%)0.020.0080.0620.59
 Diabetes mellitus, n (%)2 (3.51%)3 (5.26%)5 (8.2%)0.61n.a.n.a.n.a.
 Hypertension, n (%)6 (10.53%)11 (19.3%)19 (31.15%)0.030.290.0070.20
 Metabolic syndrome, n (%)4 (7.02%)4 (7.02%)11 (18.03%)0.10n.a.n.a.n.a.
 Depression, n (%)1 (1.75%)3 (5.26%)9 (14.75%)0.030.620.0170.13
Patient-reported symptoms and baseline clinical examination
 VAS pain (0–10), mean (±SD)2 (±2)2 (±2.39)4 (±2.35)<0.0010.97<0.001<0.001
 HAQ, mean (±SD)0 (±0.21)0 (±0.48)0 (±0.39)<0.0010.05<0.001<0.001
 Tender joints count, mean (±SD)0.37 (±1.1)0.49 (±0.98)2.98 (±4.7)<0.0010.14<0.001<0.001
 Tender enthesis count, mean (±SD)0.02 (±0.13)0.09 (±0.34)0.64 (±1.14)<0.0010.17<0.001<0.001
 PASI, mean (±SD)n.a.3.79 (±3.29)4.34 (±5.65)n.a.n.a.n.a.0.92
 NAPSI, mean (±SD)n.a.9.07 (±8.50)8.48 (±7.95)n.a.n.a.n.a.0.76
  • Joints tenderness was evaluated in 68 joints. Tender entheses count was evaluated in six sites of LEI plus bilateral quadriceps patellar insertion, proximal and distal patellar insertion and plantar fascia.

  • Values in bold signifies p value ≤0.05.

  • BMI, body mass index; HAQ, Health Assessment Questionnaire; HC, healthy control; LEI, Leeds enthesitis index; n.a., not applicable; NAPSI, Nail Psoriasis Severity Index; PASI, Psoriasis Area and Severity Index; PsA, psoriatic arthritis; PsO, psoriasis alone; PsOAr, psoriatic patients with arthralgia; VAS, Visual Analogue Scale.