Intention-to-treat analyses predicting likelihood for CMCJ surgery; crude analyses and adjusted analysis
| Crude analyses | Adjusted analysis | |||
| Or (95% CI) | P value | Or (95% CI) | P value | |
| Study group, OT-group | 0.68 (0.35 to 1.31) | 0.25 | 0.56 (0.26 to 1.21) | 0.14 |
| Age | 0.97 (0.93 to 1.01) | 1.19 | 0.97 (0.92 to 1.02) | 0.21 |
| Gender, females | 1.35 (0.59 to 3.10) | 0.48 | 1.08 (0.38 to 3.06) | 0.88 |
| Previous hand surgery, yes | 0.94 (0.41 to 2.13) | 0.88 | ||
| Previous non-pharmacological treatment, yes | 2.77 (1.29 to 5.93) | 0.009 | 2.72 (1.14 to 6.50) | 0.024 |
| Motivation for surgery (0–10, 0=no motivation) | 1.26 (1.12 to 1.41) | <0.001 | 1.25 (1.09 to 1.43) | 0.001 |
| Radiographic CMCJ OA severity: grade 0–1 (grade 0=no CMCJ OA) | 1 | |||
| grade 2 | 2.29 (0.55 to 9.52) | 0.26 | ||
| grade 3 | 1.87 (0.56 to 6.20) | 0.31 | ||
| grade 4 | 1.56 (0.46 to 5.27) | 0.47 | ||
| Presence of clinical CMCJ subluxation, yes | 0.91 (0.45 to 1.87) | 0.80 | ||
| Painful joints (MCPJ, IP, PIPJ, DIPJ: 0–14 joints) | 1.11 (0.99 to 1.24) | 0.070 | 1.10 (0.95 to 1.27) | 0.22 |
| Flexion deficit second to fifth fingers, mm | 0.99 (0.98 to 1.01) | 0.39 | ||
| Abduction CMCJ, degrees | 0.96 (0.93 to 1.00) | 0.059 | 0.97 (0.93 to 1.02) | 0.20 |
| Grip strength referred hand (% of normal grip strength) | 0.99 (0.98 to 1.00) | 0.090 | 1.00 (0.98 to 1.02) | 0.90 |
| Pain following measure of grip strength (0–10, 0=no pain) | 1.15 (1.00 to 1.32) | 0.051 | 1.05 (0.89 to 1.23) | 0.59 |
| Hand activity performance (1–4, 1=no activity problems) | 1.45 (0.67 to 3.12) | 0.35 | ||
| Disabilities of the arm, shoulder and hand (0–100, 0=no disability) | 1.02 (1.00 to 1.04) | 0.060 | 1.00 (0.97 to 1.02) | 0.81 |
Motivation for surgery is self-reported using numeric rating scale (NRS 0–10, 0=no motivation). Radiographic carpometacarpal joint osteoarthritis (CMCJ OA) severity is classified using modified Kellgren-Lawrence grade (KLG) scale (grades 0–4, 0=no CMCJ OA). Pain is self-reported using numeric rating scale (NRS 0–10, 0=no pain). Grip strength is measured in Newton (N) using the Grippit electronic instrument. Abduction CMCJ is measured in degrees using the Pollexograph. Flexion deficit is measured in millimetres. Activity performance is measured with mean score of MAP-Hand (1–4, 1= no activity problems). Disabilities of the arm, shoulder and hand is measured using sum score of QuickDASH (0–100, 0=no disability).
DIPJ, distal interphalangeal joints; IP, thumb interphalangeal joint; MCPJ, metacarpophalangeal joint; PIPJ, proximal interphalangeal joints.