Table 3

Univariate analysis for predictors of discordance in onset comparing concordant onset with longer patient-reported and physician-reported symptom durations, respectively (days; negative towards longer patient-reported duration; bolded p<0.05)

Variable	Longer patient-reported symptom		Longer MD-reported symptom
	Coefficient	95% CI	Coefficient	95% CI
Age	0.731	−0.741 to 2.203	−0.076	−0.163 to 0.011
Female	−5.215	−54.104 to 43.674	1.914	−0.954 to 4.782
Caucasian	66.903	9.710 to 124.09	0.215	−3.154 to 3.584
Education>high school	7.672	−36.236 to 51.580	0.696	−1.978 to 3.371
Income >US$50 000	81.758	15.658 to 147.858	0.480	−3.190 to 4.149
Smoking
Never	10.839	−34.052 to 55.729	0.890	−1.744 to 3.523
Past smoker	28.732	−17.007 to 74.470	−0.030	−2.708 to 2.687
Current smoker	−65.606	−124.150 to 7.062	−1.464	−4.899 to 1.971
# of comorbidities	0.234	−11.370 to 11.839	0.149	−0.533 to 0.831
Fibromyalgia	−328.138	−481.394 to 174.882	−0.865	−10.586 to 8.856
Osteoarthritis	−107.260	−176.206 to 38.313	−0.099	−4.172 to 3.975
RF positive	−5.892	−54.126 to 42.342	4.231	1.448 to 7.013
ACPA positive	3.959	−47.743 to 55.661	2.503	−0.393 to 5.398
ACPA titre	−0.168	−0.365 to 0.029	0.005	−0.006 to 0.015
Erosions	−32.970	−89.189 to 23.248	1.047	−2.232 to 4.326
DAS28	5.372	−10.357 to 21.101	0.066	−0.842 to 0.974
Swollen joint count	1.654	−2.026 to 5.334	−0.067	−0.283 to 0.150
Tender joint count	1.458	−1.903 to 4.819	−0.053	−0.251 to 0.145
HAQ	1.666	−29.965 to 33.296	0.954	−0.904 to 2.812
ESR	0.937	−0.139 to 2.013	−0.006	−0.066 to 0.054
CRP	0.406	−0.821 to 1.633	0.028	−0.043 to 0.099
MD global score	−3.770	−12.718 to 5.178	0.538	0.019 to 1.058
Patient global score	−6.316	−13.947 to 1.315	0.232	−0.214 to 0.678
CDAI	0.264	−1.333 to 1.862	0	−0.093 to 0.093
SDAI	0.552	−0.984 to 2.088	0.005	−0.087 to 0.097
Oral steroid	70.722	22.155 to 119.288	−1.833	−4.658 to 0.992
Parenteral steroid	45.731	−3.816 to 95.278	−0.980	−3.881 to 1.922
Initial RA treatment
MTX monotherapy	−0.346	−50.228 to 49.536	−1.529	−4.472 to 1.413
MTX combination	57.614	12.283 to 102.944	−0.165	−2.806 to 2.477
Other DMARDs	−85.503	−139.369 to 25.636	−0.853	−2.526 to 4.232
Biologic	66.117	−95.118 to 227.353	−3.026	−12.847 to 6.795
None of the above	−21.597	−87.697 to 44.503	2.440	−1.504 to 6.384

ACPA, anticitrullinated protein antibodies; CDAI, Clinical Disease Activity Index; CRP, C reactive protein; DAS28, Disease Activity Score based on 28 joint count; DMARD, disease-modifying antirheumatic drug; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; MD, medical doctor; MTX, methotrexate; RF, rheumatoid factor; SDAI, Simplified Disease Activity Index.