Table 3

Results of a subanalysis of 1220 patients with rheumatoid arthritis (RA)

NAll-cause mortality at 30 days n (%)HRs 30-day mortalityAll-cause mortality at 90 days n (%)HRs 90-day mortality
CrudeAdjusted*Adjusted†CrudeAdjusted*Adjusted†
CRP <8 mg/L1065 (4.7)1 (ref)1 (ref)1 (ref)6 (5.7)1 (ref)1 (ref)1 (ref)
CRP ≥8–19.9 mg/L20714 (6.8)1.45 (0.52 to 4.01)1.42 (0.51 to 3.95)1.42 (0.51 to 3.95)20 (9.7)1.74 (0.70 to 4.33)1.68 (0.69 to 4.18)1.68 (0.67 to 4.18)
CRP ≥20 mg/L39170 (17.9)4.03 (1.63 to 9.99)3.56 (1.43 to 8.85)3.64 (1.46 to 9.08)110 (28.1)5.58 (2.45 to 12.69)4.98 (2.19 to 11.36)4.91 (2.15 to 11.22)
CRP (increase by 10)70489 (12.6)1.04 (1.02 to 1.06)1.04 (1.02 to 1.06)1.04 (1.02 to 1.06)136 (19.3)1.04 (1.03 to 1.06)1.04 (1.02 to 1.06)1.04 (1.02 to 1.06)
Platelets <350×109/L41448 (11.6)1 (ref)1 (ref)1 (ref)68 (16.4)1 (ref)1 (ref)1 (ref)
Platelets 350–400×109/L9715 (15.5)1.36 (0.76 to 2.43)1.38 (0.77 to 2.49)1.39 (0.77 to 2.49)23 (23.7)1.50 (0.94 to 2.41)1.55 (0.96 to 2.50)1.54 (0.95 to 2.48)
Platelets ≥400×109/L17027 (15.9)1.40 (0.87 to 2.24)1.41 (0.88 to 2.27)1.42 (0.88 to 2.28)49 (28.8)1.84 (1.28 to 2.66)1.87 (1.29 to 2.71)1.84 (1.27 to 2.66)
Platelets (increase by 20)68190 (13.2)1.01 (0.98 to 1.04)1.02 (0.99 to 1.04)1.02 (0.99 to 1.04)140 (20.6)1.03 (1.01 to 1.05)1.03 (1.01 to 1.05)1.03 (1.01 to 1.05)
  • HRs, including 95% CI, were calculated using a Cox proportional hazards model. CRP levels and platelet counts were measured 30–90 days prior to pneumonia admission

  • All-cause mortality in patients with RA following hospitalisation for pneumonia according to disease activity measured by CRP levels and platelet counts within 30–90 days before pneumonia hospitalisation.

  • *Adjusted for sex, age, level of comorbidity, alcoholism and antibiotic use before admission.

  • †Adjusted for sex, age, level of comorbidity, alcoholism, antibiotic use and prednisolone use before admission.

  • CRP, C reactive protein.