Changes in DAS28 parameters from baseline to 3-month and 6-month follow-up visit, among RA patients in the Swedish Rheumatology Quality Register (SRQ)
| Patients with complete information at 3-month follow-up (n=4 831) | Patient with complete information at 6-month follow-up (n=4 010) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| AITD+ n=530 | AITD− n=4 301 | Mean difference Estimate (β) | 95% CI | P value | AITD+ n=441 | AITD− n=3 569 | Mean difference Estimate (β) | 95% CI | P value | |
| Δpatient global, mean±SD | 27.6 (29.1) | 23.7 (29.2) | 3.23 | 0.55 to 5.90 | 0.018 | 22.0 (32.6) | 20.9 (30.2) | 0.77 | −2.31 to 3.85 | 0.6255 |
| ΔESR, mean±SD | 15.0 (22.1) | 15.1 (21.1) | −0.51 | −2.44 to 1.42 | 0.6061 | 14.2 (19.5) | 15.2 (21.7) | −1.57 | −3.73 to 0.58 | 0.1531 |
| ΔSJC, mean±SD | 5.6 (5.7) | 5.8 (5.5) | −0.13 | −0.63 to 0.37 | 0.6143 | 5.9 (6.0) | 5.9 (5.8) | −0.02 | −0.60 to 0.57 | 0.6255 |
| ΔTJC, mean±SD | 4.8 (6.0) | 4.8 (5.9) | −0.01 | −0.55 to 0.53 | 0.9742 | 4.6 (6.1) | 4.8 (6.0) | −0.22 | −0.83 to 0.39 | 0.4836 |
| ΔDAS28, mean±SD | 2.0 (1.6) | 2.0 (1.5) | 0.04 | −0.10 to 0.17 | 0.617 | 1.9 (1.6) | 2.0 (1.6) | −0.05 | −0.21 to 0.12 | 0.5626 |
| ΔHAQ, mean±SD | 0.5 (0.6) | 0.5 (0.6) | 0.03 | 0.00 to 0.11 | 0.0410 | 0.5 (0.7) | 0.5 (0.6) | 0.04 | −0.03 to 0.10 | 0.2322 |
| ΔVAS pain, mean±SD | 29.4 (32.1) | 26.3 (29.4) | 2.60 | −0.13 to 5.33 | 0.0624 | 23.8 (33.4) | 22.9 (30.5) | 0.85 | −2.27 to 3.97 | 0.5932 |
For each of the seven variables named in the first column and for each time point, the estimate (β) was provided by a linear regression model for which the variable in the first column was the dependent variable, AITD the independent variable, and age and sex used as adjustment. The estimate (β) shows how differently the two types of patients were evolving between baseline and 3/6 months. For a given variable in the first column, a positive value means that the AITD+ patients have on average evolved (decreased) more than the AITD− patients.
AITD, autoimmune thyroid disease; DAS28, 28-joint Disease Activity Score; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; RA, rheumatoid arthritis; SJC, swollen joint count; TJC, tender joint count; VAS, Visual Analogue Scale.