Clinical characteristics of men with hypogonadism
| Testosterone ≥250 ng/dL n=35 | Testosterone <250 ng/dL n=8 | P value | |
|---|---|---|---|
| Age (years, mean±SD) | 64.5±16.7 | 69.4±13 | 0.38 |
| BMI (kg/m2, mean±SD) | 26.3±2.7 | 29.4±2.3 | 0.005 |
| GC current dose (mg/day, mean±SD) | 17.7±17 | 16.9±14.7 | 0.89 |
| GC cumulative dose (g, mean± SD) | 14.1±15.8 | 10.4±9 | 0.86 |
| Intravenous GC boluses therapy, n (%) | 11 (31.4) | 2 (25) | 1 |
| Lumbar spine BMD (g/cm2) | 1.161±0.27 | 1.220±0.31 | 0.59 |
| Femoral neck BMD (g/cm2) | 0.890±0.11 | 0.898±0.12 | 0.86 |
| Total hip BMD (g/cm2) | 0.942±0.13 | 0.973±0.13 | 0.53 |
| Densitometric osteoporosis, n (%) | 6 (17.1) | 1 (12.5) | 1 |
| TBS (mean±SD) | 1.265±0.12 | 1.142±0.12 | 0.01 |
| Degraded microarchitecture, n (%) | 15 (42.9) | 7 (87.5) | 0.046 |
| GFR (mL/min, mean±SD)* | 83.0±11.9 | 74.9±21.3 | <0.001 |
| ESR (mm/hour, mean±SD) | 12.3±14.2 | 23.1±12.7 | 0.005 |
| CRP (mg/dL, mean±SD) | 0.49±1 | 0.88±1.2 | 0.09 |
| PINP (ng/mL) | 32.1±22.4 | 19.6±8.9 | 0.09 |
| CTx (ng/mL) | 0.31±0.19 | 0.25±0.11 | 0.67 |
| 25-hydroxyvitamin D (ng/mL) | 27.8±113.3 | 22.1±7.5 | 0.39 |
*Age-adjusted values.
BMD, bone mineral density; BMI, body mass index; CRP, Creactive protein; CTx, C-terminal telopeptide of type I collagen; ESR, erythrocyte sedimentation rate; GC, glucocorticoid; GFR, glomerular filtration rate; PINP, procollagen type I N-terminal propeptide; TBS, trabecular bone score