Vertebral fractures | Fragility fractures | |||
---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
Hypogonadism | 12.38 (1.85 to >100) | 0.01 | 7.03 (1.47 to 38.37) | 0.01 |
Intravenous GC boluses therapy | 3.45 (1.04 to 12.15) | 0.01 | 1.58 (0.55 to 4.50) | 0.13 |
Densitometric osteoporosis | 2.59 (0.49 to 16.27) | 0.37 | 1.45 (0.45 to 4.55) | 0.34 |
Degraded microarchitecture | 2.36 (0.51 to 12.97) | 0.06 | 1.65 (0.48 to 6.05) | 0.12 |
FRAX for major OP fracture ≥20 | 4.56 (0.82 to 27.34) | 0.08 | 7.08 (1.28 to 53.71) | 0.02 |
Creatinine values | 3.12 (0.60 to 19.90) | 0.17 | – | – |
Glomerular filtration rate | 1.01 (0.94 to 1.08) | 0.54 | 1.01 (0.98 to 1.05) | 0.80 |
Age ≥65 years | 0.66 (0.08 to 6.75) | 0.67 | 0.62 (0.13 to 3.39) | 0.64 |
CRP | 1.03 (0.71 to 1.39) | 0.39 | 1.09 (0.83 to 1.43) | 0.24 |
The analysis was adjusted for age (analysing the data according to age <50, between 50–65 and ≥66 years), BMI, CRP and gender.
BMI, body mass index; CRP, C reactive protein; fragility fractures (VF+non-VF); GC, glucocorticoid; OP, osteoporosis; VF, vertebral fractures.