Table 3

Multivariate analysis of the risk factors for fractures

Vertebral fracturesFragility fractures
OR (95% CI)P valueOR (95% CI)P value
Hypogonadism 12.38 (1.85 to >100) 0.01 7.03 (1.47 to 38.37) 0.01
Intravenous GC boluses therapy 3.45 (1.04 to 12.15) 0.01 1.58 (0.55 to 4.50)0.13
Densitometric osteoporosis2.59 (0.49 to 16.27)0.371.45 (0.45 to 4.55)0.34
Degraded microarchitecture2.36 (0.51 to 12.97)0.061.65 (0.48 to 6.05)0.12
FRAX for major OP fracture ≥204.56 (0.82 to 27.34)0.08 7.08 (1.28 to 53.71) 0.02
Creatinine values3.12 (0.60 to 19.90)0.17
Glomerular filtration rate1.01 (0.94 to 1.08)0.541.01 (0.98 to 1.05)0.80
Age ≥65 years0.66 (0.08 to 6.75)0.670.62 (0.13 to 3.39)0.64
CRP1.03 (0.71 to 1.39)0.391.09 (0.83 to 1.43)0.24
  • The analysis was adjusted for age (analysing the data according to age <50, between 50–65 and ≥66 years), BMI, CRP and gender.

    BMI, body mass index; CRP, C reactive protein; fragility fractures (VF+non-VF); GC, glucocorticoid; OP, osteoporosis; VF, vertebral fractures.