Demographic, clinical, hepatic biological, and EDX data at the first evaluation, presented from the mildest to the severest
| Case Number | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
| Baseline characteristics | ||||||
| Age | 33 | 41 | 51 | 37 | 57 | 48 |
| Work | Physiotherapist | Engineer | Train driver trainer | Removal man | University teacher | Winegrower |
| Body Mass Index (kg/m2) | 20.8 | 21.7 | 26.9 | 24.2 | 29.1 | 25.7 |
| Gender | M | M | M | M | F | M |
| ALAT ASAT | | 200 N 80 N | 7 N 4 N | 16 N 4 N | 2 N 4 N | 10 N 5 N |
| Hepatic symptoms | None | Icterus and poor general state | None | Loss of weight (8 kgs) | None | None |
| HEV testing | ||||||
| Delay before blood testing | 15 days | 5 days | 3 months | 2 months | 3 months | 4 months |
| HEV IgM status (Wantai) | Positive | Positive | Positive | Positive | Positive | Positive |
| HEV RT-PCR | / | Positive | / | Negative | Negative | Negative |
| Clinical data: | ||||||
| Pain (NRS) | 3/10 | 4/10 | 4/10 | 6/10 | 5/10 | 6/10 |
| Initial muscle motor deficiency (MRC scale) | - left IS: 1/5 | - right SA: 4/5 - right upper T: 4/5 - right lower T: 1/5 - right IS: 4/5 - right deltoid: 4/5 - right biceps: 4/5 | - right SA: 1/5 - right SSp: 4/5 - right IS: 4/5 - right deltoid: 4/5 - right elbow flexors: 3/5 | - right SA: 1/5 - right IS: 3/5 - right FPL: 2/5 - left FPL/FDP2/PQ: 2/5 | - right SA: 2/5 - IS: right 4/5, left 1/5 - left T: 4/5 - right FPL/FDP/PQ: 2/5 - left FPL/FDP/PQ: 3/5 | - T: right 1/5, left 3/5 - SA: right 1/5, left 4/5 - IS: right 1/5, left: 2/5 - right FPL: 1/5 - left FPL: 3/5 - right FDP2: 1/5 - right PQ: 0/5 - left PQ: 3/5 - bilat diaphragm: orthopnoea requiring oxygen at night |
| EDX data | ||||||
| Time since onset in months | 3 | 1 | 3 | 6 | 3 | 3 |
| EDX: importance of the initial nerve lesions | - severe left SSN | - severe right LTN - important right SAN - mild right SSN | - severe right LTN - moderate upper trunk of BP (C5C6C7) or C5C6C7 root entrapment | - important right LTN - moderate right SSN - moderate left LABCN - important bilat AIN | - obvious right LTN - obvious right sensory fibre of median nerve - severe left SSN - mild left C7 - important right & moderate left AIN | - severe right & mild left LTN - severe right & moderate left AIN - severe bilat SSN - severe bilat SAN - severe bilat PN |
| MRI data | ||||||
| Cervical MRI data | / | No radicular impingement | Narrowing of the cervical spine canal | No radicular impingement | Left C7 impingement | No radicular impingement |
| Scapular MRI data | ||||||
| Time since onset | / | 3 years | 6 months | 8 months | 6 months | 10 months |
| Scapular MRI | / | - hyperT1*: right SA - amyotrophy right SA | - hyperT1: right TM - hyperT2 Dixon†: right SA/Deltoid - amyotrophy: right SA/Deltoid/TM/BB/IS/SSc | - hyperT2 Dixon: right SA - amyotrophy right SA | - hyperT1: both SA - hyperT2: left IS/SSp, - amyotrophy: left IS/SSp - hyperT2 Dixon: PQ/FDP/AM on left arm MRI | - hyperT2 Dixon: both T, both IS, right SA - amyotrophy: both SSp |
*HyperT1 signal: muscle fatty infiltration.
†HyperT2 Dixon signal: muscle oedema.
/, Missing data.
AM, Anconeal muscle; ASAT, Aspartate aminotransferase; ALAT, Alanine aminotransferase, AIN, Anterior interosseous nerve; BP, Brachial plexus; bilat, bilateral, CMAP, Compound motor action potential; FPL: flexor pollicis longus; FDP2, Flexor digitorum profundus of digit 2; HEV, Hepatitis E virus; IS, Infraspinatus; LTN, Long thoracic nerve; LABCN, Lateral antebrachial cutaneous nerve; NRS, Numeric rating scale; PQ: Pronator quadratus; PN, Phrenic nerve; RT-PCR, reverse transcription PCR; SSN, Suprascapular nerve; SAN, Spinal acccessory nerve; SA, Serratus anterior; SSp, Supraspinatus; T, Trapezius.