Table 1

Demographic, clinical, hepatic biological, and EDX data at the first evaluation, presented from the mildest to the severest

Case Number123456
Baseline characteristics
Age334151375748
WorkPhysiotherapistEngineerTrain driver trainerRemoval manUniversity teacherWinegrower
Body Mass Index
(kg/m2)
20.821.726.924.229.125.7
GenderMMMMFM
ALAT
ASAT

200 N
80 N
7 N
4 N
16 N
4 N
2 N
4 N
10 N
5 N
Hepatic symptomsNoneIcterus and poor general stateNoneLoss of weight (8 kgs)NoneNone
HEV testing
Delay before blood testing15 days5 days3 months2 months3 months4 months
HEV IgM status
(Wantai)
PositivePositivePositivePositivePositivePositive
HEV RT-PCR/Positive/NegativeNegativeNegative
Clinical data:
Pain (NRS)3/104/104/106/105/106/10
Initial muscle motor deficiency
(MRC scale)
- left IS: 1/5- right SA: 4/5
- right upper T: 4/5
- right lower T: 1/5
- right IS: 4/5
- right deltoid: 4/5
- right biceps: 4/5
- right SA: 1/5
- right SSp: 4/5
- right IS: 4/5
- right deltoid: 4/5
- right elbow flexors: 3/5
- right SA: 1/5
- right IS: 3/5
- right FPL: 2/5
- left FPL/FDP2/PQ: 2/5
- right SA: 2/5
- IS: right 4/5, left 1/5
- left T: 4/5
- right FPL/FDP/PQ: 2/5
- left FPL/FDP/PQ: 3/5
- T: right 1/5, left 3/5
- SA: right 1/5, left 4/5
- IS: right 1/5, left: 2/5
- right FPL: 1/5
- left FPL: 3/5
- right FDP2: 1/5
- right PQ: 0/5
- left PQ: 3/5
- bilat diaphragm: orthopnoea requiring oxygen at night
EDX data
Time since onset in months313633
EDX: importance of the initial nerve lesions- severe left SSN- severe right LTN
- important right SAN
- mild right SSN
- severe right LTN
- moderate upper trunk of BP (C5C6C7) or C5C6C7 root entrapment
- important right LTN
- moderate right SSN
- moderate left LABCN
- important bilat AIN
- obvious right LTN
- obvious right sensory fibre of median nerve
- severe left SSN
- mild left C7
- important right & moderate left AIN
- severe right & mild left LTN
- severe right & moderate left AIN
- severe bilat SSN
- severe bilat SAN
- severe bilat PN
MRI data
Cervical MRI data/No radicular impingementNarrowing of the cervical spine canalNo radicular impingementLeft C7 impingementNo radicular impingement
Scapular MRI data
Time since onset/3 years6 months8 months6 months10 months
Scapular MRI/- hyperT1*: right SA
- amyotrophy right SA
- hyperT1: right TM
- hyperT2 Dixon†: right SA/Deltoid
- amyotrophy: right SA/Deltoid/TM/BB/IS/SSc
- hyperT2 Dixon: right SA
- amyotrophy right SA
- hyperT1: both SA
- hyperT2: left IS/SSp,
- amyotrophy: left IS/SSp
- hyperT2 Dixon: PQ/FDP/AM on left arm MRI
- hyperT2 Dixon: both T, both IS, right SA
- amyotrophy: both SSp
  • *HyperT1 signal: muscle fatty infiltration.

  • †HyperT2 Dixon signal: muscle oedema.

  • /, Missing data.

  • AM, Anconeal muscle; ASAT, Aspartate aminotransferase; ALAT, Alanine aminotransferase, AIN, Anterior interosseous nerve; BP, Brachial plexus; bilat, bilateral, CMAP, Compound motor action potential; FPL: flexor pollicis longus; FDP2, Flexor digitorum profundus of digit 2; HEV, Hepatitis E virus; IS, Infraspinatus; LTN, Long thoracic nerve; LABCN, Lateral antebrachial cutaneous nerve; NRS, Numeric rating scale; PQ: Pronator quadratus; PN, Phrenic nerve; RT-PCR, reverse transcription PCR; SSN, Suprascapular nerve; SAN, Spinal acccessory nerve; SA, Serratus anterior; SSp, Supraspinatus; T, Trapezius.