Table 4

Multivariable logistic regression model with MDA at T6 as outcome and Cox regression model with time-to-SEC withdrawal as outcome

Independent variablesMDA at T6Time to SEC withdrawal
Multivariable analysisMultivariable analysis
OR (95% CI)P valueHR (95% CI)P value
Male sex1.60 (1.05 to 2.45)0.0280.68 (0.48 to 0.97)0.032
Age0.99 (0.98 to 1.02)0.8921.01 (0.98 to 1.02)0.704
Smoking1.12 (0.70 to 1.80)0.6261.15 (0.78 to 1.69)0.475
Psoriasis1.31 (0.83 to 2.06)0.2401.07 (0.73 to 1.58)0.720
Bio-naïve0.93 (0.55 to 1.55)0.7861.20 (0.78 to 1.86)0.397
Dosage SEC 300 mg1.67 (0.41 to 1.11)0.1231.82 (0.36 to 0.84)0.006
BMI1.02 (0.97 to 1.06)0.4611.04 (1.01 to 1.07)0.015
csDMARDs at T00.62 (0.41 to 0.95)0.0301.87 (1.18 to 2.80)0.417
DAPSA at T00.94 (0.92 to 0.96)0.0101.00 (0.98 to 1.01)0.638
  • P0.05.

  • The bold allows to highlight the values in which a statistical significance has been obtained.

  • Bio-naïve, first biological treatment line; BMI, body mass index; Coeff, coefficient; csDMARDs, conventional synthetic disease-modifying antirheumatic drugs; DAPSA, Disease Activity Index for Psoriatic Arthritis; MDA, minimal disease activity; SEC, secukinumab; T6, 6 months.