Quintile | Total population | GPA <65 (n) | Crude rate <65 | GPA >65 (n) | Crude rate >65 | Overall direct standardised rate (95% CI) | SIR (95% CI) |
(A) Granulomatosis with polyangiitis | |||||||
1 | 855 118 | 19 | 5.5 | 8 | 9.6 | 6.4 (4.0 to 8.8) | 143 (94 to 207) |
2 | 876 250 | 8 | 2.4 | 16 | 16.2 | 5.4 (3.2 to 7.5) | 116 (74 to 173) |
3 | 906 595 | 13 | 3.8 | 13 | 12.2 | 5.6 (3.4 to 7.7) | 119 (77 to 174) |
4 | 919 736 | 15 | 4.2 | 15 | 14.2 | 6.4 (4.1 to 8.7) | 137 (92 to 196) |
5 | 931 084 | 9 | 2.5 | 13 | 12.4 | 4.7 (2.7 to 6.6) | Ref |
(B) Microscopic polyangiitis | |||||||
Quintile | Total population | MPA <65 (n) | Crude rate <65 | MPA >65 (n) | Crude rate >65 | Overall direct standardised rate (95% CI) | SIR (95% CI) |
1 | 855 118 | 11 | 3.2 | 21 | 25.2 | 8.0 (5.2 to 10.8) | 74 (51 to 104) |
2 | 876 250 | 17 | 5.0 | 29 | 29.4 | 10.3 (7.3 to 13.3) | 96 (70.3 to 128) |
3 | 906 595 | 17 | 4.9 | 19 | 17.8 | 7.7 (5.2 to 10.2) | 71 (45 to 98) |
4 | 919 736 | 17 | 4.8 | 23 | 21.8 | 8.5 (5.9 to 11.1) | 79 (56 to 107) |
5 | 931 084 | 17 | 4.7 | 34 | 32.4 | 10.8 (7.8 to 13.8) | Ref |
SIMD quintile of deprivation: Q1=most deprived, Q5=least deprived. Crude rate is number of cases in each quintile, adjusted for underlying age distribution within that quintile, per million population per year. Direct standardised rate=rate of disease within each quintile adjusted for overall Scottish age distribution. SIR = Standardised incidence ratio (95% confidence interval) for each quintile, compared with Q5 (reference group).
AAV, ANCA-associated vasculitis; GPA, granulomatosis polyangiitis; MPA, microscopic polyangiitis; SIMD, Scottish Index of Multiple Deprivation; SIR, standardised incidence ratio (95% CI) for each quintile, compared with Q5 (reference group).