Table 3

Incidence of kidney biopsy-proven AAV by quintiles of deprivation and calculated standardised incidence ratio

QuintileTotal populationGPA <65 (n)Crude rate
<65
GPA >65 (n)Crude rate
>65
Overall direct standardised rate (95% CI)SIR (95% CI)
(A) Granulomatosis with polyangiitis
1855 118195.589.66.4 (4.0 to 8.8)143 (94 to 207)
2876 25082.41616.25.4 (3.2 to 7.5)116 (74 to 173)
3906 595133.81312.25.6 (3.4 to 7.7)119 (77 to 174)
4919 736154.21514.26.4 (4.1 to 8.7)137 (92 to 196)
5931 08492.51312.44.7 (2.7 to 6.6)Ref
(B) Microscopic polyangiitis
QuintileTotal populationMPA <65 (n)Crude rate <65MPA >65 (n)Crude rate >65Overall direct standardised rate (95% CI)SIR (95% CI)
1855 118113.22125.28.0 (5.2 to 10.8)74 (51 to 104)
2876 250175.02929.410.3 (7.3 to 13.3)96 (70.3 to 128)
3906 595174.91917.87.7 (5.2 to 10.2)71 (45 to 98)
4919 736174.82321.88.5 (5.9 to 11.1)79 (56 to 107)
5931 084174.73432.410.8 (7.8 to 13.8)Ref
  • SIMD quintile of deprivation: Q1=most deprived, Q5=least deprived. Crude rate is number of cases in each quintile, adjusted for underlying age distribution within that quintile, per million population per year. Direct standardised rate=rate of disease within each quintile adjusted for overall Scottish age distribution. SIR = Standardised incidence ratio (95% confidence interval) for each quintile, compared with Q5 (reference group).

  • AAV, ANCA-associated vasculitis; GPA, granulomatosis polyangiitis; MPA, microscopic polyangiitis; SIMD, Scottish Index of Multiple Deprivation; SIR, standardised incidence ratio (95% CI) for each quintile, compared with Q5 (reference group).