Comparison of clinical variables between baseline and T6 (6 months)
| Clinical variables | T0 | T6 | P value |
| Faecal calprotectin (μg/g)—median (IQR) | 207.5 (125.5–446.2) | 81 (50–197.2) | 0.004 |
| CRP (mg/L)—median (IQR) | 8.2 (4.8–20.8) | 2.9 (1–4) | 0.001 |
| ESR (mm/hour)—median (IQR) | 21.5 (10.8–34) | 11 (7.8–21) | 0.003 |
| VAS_pain—median (IQR) | 50 (38.8–60) | 35 (10–42.5) | 0.001 |
| VAS_disease—median (IQR) | 50 (38.8–50) | 37.5 (25–42.5) | 0.006 |
| HAQ—mediana (IQR) | 0.6 (0.1–0.8) | 0.2 (0.1–0.6) | 0.004 |
| BASDAI_score—median (IQR) | 5.2 (4.1–5.6) | 2.8 (2.5–4.3) | 0.013 |
| CDAI_activity—median (IQR) | 13 (10.5–16) | 7 (5.2–11) | 0.004 |
| IBD activity, n (%)—0 | 11 (55) | 20 (100) | 0.174 |
| IBD activity, n (%)—1 | 6 (30) | 0 (0) | |
| IBD activity, n (%)—2 | 2 (10) | 0 (0) | |
| IBD activity, n (%)—3 | 1 (5) | 0 (0) |
BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; CDAI, Clinical Disease Activity Index; CRP, C reactive protein; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; IBD, inflammatory bowel diseases; VAS, Visual Analogue Scale.