Adverse events and disease flares after COVID-19 vaccination, reported by patients to be severe and lasting at least 2 days
| All n=2860 | Pfizer-BioNTech n=1522 | Oxford/AstraZeneca n=645 | Moderna n=610 | Janssen/Johnson & Johnson n=50 | Others* n=33 | |
| Any adverse events | 1350 (47.2) | 648 (42.6) | 335 (51.9) | 327 (53.6) | 30 (60.0) | 10 (30.3) |
| Fatigue or sleepiness | 955 (33.4) | 455 (29.9) | 229 (35.5) | 245 (40.2) | 22 (44.0) | 4 (12.1) |
| Headache | 792 (27.7) | 350 (23.0) | 218 (33.8) | 196 (32.1) | 23 (46.0) | 5 (15.2) |
| Widespread muscle/Joint pain | 653 (22.8) | 294 (19.3) | 166 (25.7) | 176 (28.9) | 17 (34.0) | 0 (0) |
| Fever or chills | 568 (19.9) | 214 (14.1) | 167 (25.9) | 170 (27.9) | 16 (32.0) | 1 (3.0) |
| Anaphylaxis† | 6 (0.2) | 2 (0.1) | 1 (0.2) | 1 (0.2) | 1 (2.0) | 1 (3.0) |
| Other‡ | 204 (7.1) | 86 (5.7) | 49 (7.6) | 64 (10.5) | 4 (8.0) | 1 (3.0) |
| Nausea or vomiting | 364 (12.7) | 167 (11.0) | 90 (14.0) | 101 (16.6) | 6 (12.0) | 0 (0) |
| Any flare of rheumatic disease§ | 382 (13.4) | 184 (12.1) | 93 (14.4) | 96 (15.7) | 7 (14.0) | 2 (6.1) |
| Flare requiring new or increased dose of medication§ | 132 (4.6) | 58 (3.8) | 40 (6.2) | 32 (5.2) | 2 (4.0) | 0 (0) |
*Includes Novavax, Sinovac/Sinopharm, Sputnik V, Cansino, not sure and others.
†Anaphylaxis was not required to last 2 days.
‡Including chest pain/palpitations, other allergic reactions and rash.
§Exacerbation of symptoms or new symptoms attributed to underlying systemic rheumatic disease.