Table 1

Research articles identified by the literature search according to the different at-risk populations

Risk factorAt-risk populationTotal
Asymptomatic*MSK symptoms without clinical arthritisUA/PR
Subclinical inflammation on ultrasound08412
Subclinical inflammation on MRI0426
ACPA/RF/Other autoantibodies64313
Clinical features04913
Demographic features0101
Serum markers1214
Cellular markers0202
Genetic markers0112
  • Fifty-three articles were identified: one article reported on both clinical and genetic risk factors; one article reported on both autoantibodies and serum markers.

  • *Including relatives of patients with RA.

  • ACPA, anticitrullinated protein antibodies; BMD, bone mineral density; MSK, musculoskeletal; PR, palindromic rheumatism; RA, rheumatoid arthritis; RF, rheumatoid factor; UA, undifferentiated arthritis.