Table 1

Distribution and clinical characteristics of patients with and without amyloidosis in the SpA and non-SpA cohorts

SpA without amyloidosisSpA and amyloidosisP valueSpA and amyloidosisNon-SpA and amyloidosisP value
N (%) 106 348 (100) 792 (100) 792 (100) 68 (100)
Mean age (SD) 58.9 (15.4) 55.8 (13.1)<0.001 55.8 (13.1) 65.4 (13.2)<0.001
Mean Charlson index (SD) 1.14 (1.81) 1.80 (1.34)<0.001 1.80 (1.34) 1.69 (1.18) 0.477
Average length of stay in days (SD) 10.5 (15.3) 12.7 (15.1)<0.001 12.7 (15.1) 10.3 (8.9)0.038
Male n (%) 70 792 (66.5) 596 (75.2)<0.001 596 (75.2) 43 (58.1)0.002
Death during admission, n (%) 3537 (3.3) 82 (10.3)<0.001 82 (10.3) 5 (6.8) 0.329
Ankylosing spondylitis (%) 67 207 (63.1) 538 (67.9)<0.001 538 (67.9)NA
Psoriatic arthritis (%) 37 673 (35.4) 243 (30.6)0.005 243 (30.6)NA
Spondyloarthritis-associated inflammatory bowel disease (%) 5238 (4.9) 81 (10.2)<0.001 81 (10.2)NA
Reactive arthritis (%) 2178 (2.0) 20 (2.5) 0.318 20 (2.5)NA
Uveitis (%) 542 (0.5) 12 (1.5)<0.001 12 (1.5) 0 (0)
Diabetes mellitus (%) 14 822 (13.9) 34 (4.3)<0.001 34 (4.3) 5 (6.8) 0.378
Dementia (%) 626 (0.6) 3 (0.4) 0.638 3 (0.4) 3 (4.1) 0.01
Hypertension (%) 31 395 (29.5) 185 (23.3)<0.001 185 (23.3) 16 (21.6) 0.886
Smoking (%) 13 283 (12.4) 56 (7.1)<0.001 56 (7.1) 3 (4.1) 0.469
Hyperlipidaemia (%) 17 748 (16.6) 99 (12.5)<0.001 99 (12.5) 15 (20.3) 0.071
Obesity (%) 1323 (1.2) 3 (0.4)0.023 3 (0.4) 0 (0) 0.1
Deep vein thrombosis (%) 648 (0.6) 7 (0.9) 0.351 7 (0.9) 1 (1.4) 0.512
Depression (%) 5939 (5.6) 23 (2.9)<0.001 23 (2.9) 6 (8.1)0.031
Tuberculosis (%) 544 (0.5) 3 (0.4) 0.803 3 (0.4) 1 (1.4) 0.416
  • bold, p<0.05; SpA, spondyloarthritis.