Table 5

Risk of amyloidosis associated with SpA and subtypes of SpA

Without amyloidosisWith amyloidosisCrude OR95% CIAOR95% CI
N (%)213 414 (99.6)860 (0.4)
Non-SpA (%)107 066 (99.9)68 (0.1)refref
SpA (%)106 348 (99.3)792 (0.7)10.78.413.610.48.213.3
AS (%)61 837 (99.3)454 (0.7)10.68.313.510.07.812.8
PsA (%)37 132 (99.4)237 (0.6)9.27.111.99.57.312.4
SpA-IBD (%)5238 (98.5)81 (1.5)22.316.330.722.916.631.7
ReA (%)2141 (99.1)20 (0.9)13.58.222.110.16.116.7
  • OR adjusted by: sex, age, year of admission, Charlson index, readmission, infectious diseases, cardiovascular disease, hypertension, smoking, diabetes mellitus, HCV, HBV, depression, obesity, tuberculosis, osteoporosis, axial surgery and uveitis.

  • AOR, adjusted OR; AS, ankylosing spondylitis; PsA, psoriatic arthritis; ReA, reactive arthritis; SpA, spondyloarthritis; SpA-IBD, SpA-associated inflammatory bowel disease.