Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 | Patient 9 | Patient 10 | |
CV outcome | SVT | SVT | AF | AF | AF and flutter | Atrial flutter | NSVT | NSVT | NSVT | Myocarditis systolic dysfunction |
Baseline ECG | – | SR | SR | SR | SR | SR | SR | SR, VE | SR, unspecific flattened T wave | SR |
Age (years) | 74 | 62 | 57 | 73 | 49 | 55 | 52 | 59 | 50 | 60 |
Gender | F | F | F | F | F | F | F | F | M | F |
SSc subset | lcSSc | lcSSc | dcSSc | lcSSc | lcSSc | lcSSc | dcSSc | dcSSc | dcSSc | dcSSc |
ILD | No | No | No | No | No | No | Yes | Yes | Yes | Yes |
MRSS | 6 | 4 | 14 | 2 | 2 | 6 | 11 | 18 | 0 | 9 |
ANA | ACA | ACA | – | ACA | ACA | ACA | Scl70 | Anti Ro | Scl70 | Scl70 |
History of DU | Yes | No | No | No | No | Yes | No | No | No | No |
NT-proBNP (pg/mL) | 161 | 288 | 105 | 127 | 32 | 141 | 329 | 105 | 38 | 470 |
Hs-TnI (ng/L) | 3 | 5 | 3 | – | 6 | 31 | 313 | 5 | 3 | 225 |
ACA, anti-centromere antibody; AF, atrial fibrillation; ANA, antinuclear antibodies; CV, cardiovascular; dcSSc, diffuse cutaneous systemic sclerosis; DU, digital ulcers; hs-TnI, high-sensitivity troponin I; IcSSc, limited cutaneous systemic sclerosis; ILD, interstitial lung disease; MRSS, modified Rodnan skin score; NSVT, non-sustained ventricular tachycardia; NT-proBNP, N-terminal pro-brain natriuretic peptide; Scl70, anti-topoisomerase antibody; SR, sinus rhythm; SSc, systemic sclerosis; SVT, supraventricular tachycardia; VE, ventricular ectopics.