Dependent variable | Independent variable | Univariable analysis | Multivariable analysis | ||||||
β | P value | B | 95% CI | β | P value | B | 95% CI | ||
SUV-SYNmean-12 | CRP-6 | 0.499 | 0.030 | 0.042 | 0.005 to 0.080 | ||||
CRP-12 | 0.529 | 0.020 | 0.038 | 0.007 to 0.070 | |||||
Lp(a)-0 | 0.671 | 0.001 | 0.001 | 0.001 to 0.002 | |||||
Lp(a)-6 | 0.676 | 0.001 | 0.002 | 0.001 to 0.003 | |||||
Lp(a)-12 | 0.683 | 0.001 | 0.002 | 0.001 to 0.003 | 0.453 | 0.001 | 0.001 | 0.001 to 0.002 | |
CTX-12 | 0.474 | 0.041 | 2.380 | 0.115 to 4.645 | |||||
PWV-0 | 0.571 | 0.011 | 0.149 | 0.040 to 0.259 | |||||
TBR-SYNmean-12 | Lp(a)-0 | 0.547 | 0.015 | 0 | 0 to 0.001 | ||||
Lp(a)-6 | 0.567 | 0.011 | 0.001 | 0 to 0.001 | |||||
Lp(a)-12 | 0.581 | 0.009 | 0.001 | 0 to 0.001 | 0.335 | 0.016 | 0 | 0 to 0.001 | |
IMT-12 | 0.467 | 0.044 | 0.668 | 0.021 to 1.315 | |||||
DXAL24BMD-12 | −0.518 | 0.023 | −0.897 | −0.197 to −0.007 | |||||
TBR-VASCmean-12 | HAQ-6 | −0.457 | 0.049 | −0.136 | −0.271 to −0.001 | −0.542 | <0.001 | −0.161 | −0.228 to −0.094 |
DAS28-6 | 0.597 | 0.007 | 0.187 | 0.058 to 0.316 | 0.617 | <0.001 | 0.194 | 0.123 to 0.265 | |
OC-0 | 0.531 | 0.019 | 0.017 | 0.003 to 0.031 | |||||
P1NP-12 | 0.470 | 0.043 | 0.005 | 0 to 0.010 | 0.464 | 0.001 | 0.005 | 0.003 to 0.008 | |
PWV-0 | 0.526 | 0.021 | 0.069 | 0.009 to 0.098 | |||||
PWV-12 | 0.546 | 0.016 | 0.069 | 0.014 to 0.113 | |||||
TBR-VASCmax-12 | HAQ-0 | −0.529 | 0.020 | −0.291 | −0.529 to −0.052 | −0.529 | 0.020 | −0.291 | −0.529 to −0.052 |
HAQ-6 | −0.471 | 0.042 | −0.212 | −0.415 to −0.009 |
The numbers -0 and -12 indicate values at baseline and after 12 months of treatment.
BMD, bone mineral density; CRP, C reactive protein; CTX, C-terminal collagen crosslink; DAS28, 28-Joint Disease Activity Score; DXA, dual-energy X-ray absorptiometry; HAQ, health assessment questionnaire; IMT, intima–media thickness; L24, lumbar 2–4 vertebrae; Lp(a), lipoprotein A; max, maximum; OC, osteocalcin; PET, positron emission tomography; P1NP, procollagen 1 N-terminal propeptide; PWV, pulse-wave velocity; SUV, standardised uptake value; SYN, synovial; TBR, target-to-background ratio; VASC, vascular.