Patient-reported outcomes regarding physical disability, depression, anxiety, fatigue and quality of life across JIA categories
| Variable (median (IQR)) | Total | Persistent oligoarthritis | Extended oligoarthritis | RF-positive polyarthritis | RF-negative polyarthritis | Systemic | Enthesitis-related arthritis | Psoriatic arthritis | Undif. arthritis |
| HAQ | 0.13 (0; 0.8) | 0.13 (0; 0.63) | 0 (0; 0.38) | 0.5 (0; 1.06) | 0 (0; 0.5) | 0 (0; 0.75) | 0.13 (0; 0.8) | 0 (0; 0.5) | 0.5 (0; 1.13) |
| HADS-D | 2 (1; 5) | 2 (1; 4) | 2 (0; 8) | 3 (1; 10) | 2.5 (1; 5) | 1 (0; 4) | 2 (0; 4) | 0 (0; 1) | 3 (1; 7) |
| HADS-A | 4 (2; 7) | 4.5 (2; 7.5) | 5 (2; 8) | 4 (2; 6) | 5 (2; 7) | 4 (1; 6) | 3.5 (0.5; 6) | 2 (2; 6) | 6 (2; 8) |
| FACIT-F | 44 (33; 48) | 45.2 (35; 48) | 40 (26; 48) | 39.5 (31.5; 47.5) | 43.5 (36; 46) | 45 (33; 48) | 45 (39; 49.5) | 47 (44; 51) | 34 (25; 40) |
| EQ5D | 0.7 (0.5; 1) | 0.7 (0.7; 1) | 0.6 (0.5; 0.8) | 0.6 (0.3; 1) | 0.6 (0.5; 0.8) | 0.4 (0.3; 0.7) | 0.7 (0.59; 1) | 0.7 (0.7; 1) | 0.3 (0.3; 0.5) |
| EQ5D VAS | 72 (50; 90) | 75 (50; 85) | 67.5 (50; 80) | 75 (55; 90) | 80 (58; 90) | 80 (70; 80) | 75 (50; 90) | 70 (0; 80) | 60 (31; 74) |
| SF-36 PC | |||||||||
| PF | 75 (45; 95) | 90 (70; 100) | 90 (55; 95) | 70 (40; 95) | 70 (55; 85) | 55 (30; 97.5) | 85 (55; 95) | 98 (90; 100) | 40 (20; 75) |
| RP | 93.8 (38; 100) | 100 (62.5; 100) | 100 (43.8; 100) | 96.9 (25; 100) | 75 (50; 100) | 100 (66; 100) | 100 (50; 100) | 100 (100; 100) | 37.5 (25; 93.8) |
| BP | 62 (41; 84) | 74 (62; 8) | 62 (32; 84) | 72 (32; 100) | 61.5 (41; 84) | 61.5 (41; 84) | 62 (42; 84) | 84 (61.5; 92) | 51 (31; 62) |
| GH | 50 (35; 70) | 52 (40; 77) | 48.5 (37; 72) | 43.5 (30; 77) | 47.5 (35; 67) | 57 (30; 69.5) | 51 (37; 67) | 51 (43.5; 77) | 45 (25; 67) |
| SF-36 MC | |||||||||
| VT | 55 (40; 75) | 61.3 (43.8; 81.3) | 56.3 (37.5; 75) | 52.5 (40; 70) | 60 (45; 68.8) | 58.8 (34; 80.6) | 55 (45; 81) | 63.8 (61; 93) | 50 (40; 55) |
| SF | 87.5 (63; 100) | 81.3 (75; 100) | 87.5 (62.5; 100) | 87.5 (75; 100) | 87.5 (75; 100) | 100 (75; 100) | 93.8 (63; 100) | 100 (100; 100) | 50 (39; 87.5) |
| RE | 100 (63; 100) | 100 (66.7; 100) | 100 (66.7; 100) | 100 (33; 100) | 95.8 (58; 100) | 100 (50; 100) | 100 (100; 100) | 100 (100; 100) | 100 (33; 100) |
| MH | 76.4 (60; 88) | 78 (52; 90) | 75 (55; 85) | 75 (62.7; 84.5) | 80 (64; 90) | 80.7 (55; 90) | 81.4 (64; 90) | 84.5 (74; 88) | 68 (52; 86.4) |
Sample size regarding HAQ, HADS, FACIT-F, EQ5D and SF-36 is not constant due to missing data:.
HAQ: total n=551; persistent oligoarthritis n=103; extended oligoarthritis n=76; RF positive polyarthritis n=64; RF negative polyarthritis n=92; systemic n=51; enthesitis-related arthritis n=101; undifferentiated arthritis n=41
HADS: total n=210; persistent oligoarthritis n=28; extended oligoarthritis n=22; RF positive polyarthritis n=25; RF negative polyarthritis n=40; systemic n=19; enthesitis-related arthritis n=44; psoriatic arthritis n=5; undifferentiated arthritis n=25
FACIT-F: : total n=227; persistent oligoarthritis n=30; extended oligoarthritis n=26; RF positive polyarthritis n=28; RF negative polyarthritis n=42; systemic n=23; enthesitis-related arthritis n=48; psoriatic arthritis n=7; undifferentiated arthritis n=21
EQ5D and EQ5D VAS: total n=181; persistent oligoarthritis n=21; extended oligoarthritis n=22; RF positive polyarthritis n=20; RF negative polyarthritis n=35; systemic n=16; enthesitis-related arthritis n=38; psoriatic arthritis n=3; undifferentiated arthritis n=23.
SF-36 PC and SF-36 MC: total n=246; persistent oligoarthritis n=30; extended oligoarthritis n=25; RF positive polyarthritis n=32; RF negative polyarthritis n=42; systemic n=20; enthesitis-related arthritis n=50; psoriatic arthritis n=8; undifferentiated arthritis n=35.
RP- role limitations due to physical problems; Undif. Arthritis, undifferentiated arthritis; BP, intensity and discomfort caused by pain; EQ5D, EuroQol-5D; FACIT-F, Chronic Illness Therapy, Fatigue Scale; GH, general health; HADS-A, Hospital Anxiety and Depression Scale-anxiety; HADS-D, Hospital Anxiety and Depression Scale-depression; JIA, juvenile idiopathic arthritis ; SF36 MC, mental component of the Short Form 36; MH, mental health ; SF36 PC, physical component of the Short Form 36; PF, physical function; RE, role limitations due to emotional problems; ; RF, rheumatoid factor; SF, social function; VAS, Visual Analogue Scale; VT, vitality.