Cis-Eqtl effects between genetic variants associated with the level of fatigue in PSS and whole blood gene expression levels at the RTP4/MASP1 locus
| SNP | SNP position | Major/minor allele | eQTL gene | eQTL Z-score | P value* |
| rs7611640 | 3:188 561 096 | G/A | RTP4 | −6.41 | 1.4×10–10 |
| MASP1 | −3.04 | 2.4×10–3 | |||
| rs6797770 | 3:188 567 203 | T/C | RTP4 | −7.2 | 5.9×10–13 |
| MASP1 | −3.64 | 2.8×10–4 | |||
| rs1518868 | 3:188 572 262 | T/C | RTP4 | −7.33 | 2.4×10–13 |
| MASP1 | −3.56 | 3.7×10–4 |
*P value for the eQTL between the SNP and whole blood mRNA expression of RTP4, respectively, MASP1, according to Westra et al.18
eQTL, expression quantitative trait locus; MASP1, mannan binding lectin serine peptidase 1; PSS, primary Sjögren’s syndrome; RTP4, receptor transporter protein 4.