Association between signs of vessel wall inflammation and synchronous morphological vessel changes
| Total segments | Stenoses | Dilations | Stenoses or dilations | Accuracy for stenosis or dilations | ||||||||
| n | % | n | % | n | % | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | |||
| PET score=0 | 598 | 38 | 6.4 | 13 | 2.2 | 50 | 8.4 | |||||
| PET score=1 | 479 | 44 | 9.2 | 11 | 2.3 | 51 | 10.6 | PET score≥1 | 59% (50% to 68%) | 51% (48% to 54%) | 12% (10% to 15%) | 91.6% (89.1% to 93.7%) |
| PET score=2 | 55 | 3 | 5.5 | 8 | 14.5 | 11 | 20.0 | PET score≥2 | 18% (12% to 26%) | 90% (88% to 92%) | 17% (11% to 25%) | 90.6% (88.7% to 92.3%) |
| PET score=3 | 74 | 7 | 9.5 | 4 | 5.4 | 11 | 14.9 | PET score≥3 | 9% (5% to 15%) | 94% (93% to 96%) | 15% (8% to 25%) | 90.1% (88.2% to 91.8%) |
| Total | 1206 | 92 | 7.6 | 36 | 3.0 | 123 | 10.2 | |||||
| Without thickening | 971 | 41 | 4.2 | 20 | 2.1 | 60 | 6.2 | |||||
| With thickening | 235 | 51 | 21.7 | 16 | 6.8 | 63 | 26.8 | Wall thickening | 51% (42% to 60%) | 84% (82% to 86%) | 27% (21% to 33%) | 93.8% (92.1% to 93.5%) |
| Total | 1206 | 92 | 7.6 | 36 | 3.0 | 123 | 10.2 | |||||
Association between PET score and wall thickening with the presence of synchronous stenosis alone, dilations alone, and stenoses/dilations considered together.
NPV, negative predictive value; PET, positron emission tomography; PPV, positive predictive value.