Allergic condition | N (%) or median (IQR) | ||
RF +RA cases (N=2301) | Controls (N=5429) | Adjusted* OR (95% CI) for RF +RA | |
Animal dander | 62 (7) | 134 (5) | 1.47 (1.06 to 2.03) |
Allergic rhinitis | 180 (9) | 387 (8) | 1.35 (0.99 to 1.84)† |
Atopic dermatitis | 227 (11) | 453 (10) | 1.04 (0.87 to 1.23) |
Metal allergy | 28 (3) | 58 (2) | 1.25 (0.78 to 2.00) |
Respiratory allergy | 106 (11) | 271 (9) | 1.18 (0.92 to 1.51) |
Food allergy | 12 (1.3) | 40 (1.5) | 1.00 (0.52 to 1.95) |
Plants and pollen | 90 (10) | 293 (10) | 1.03 (0.79 to 1.33) |
Allergy to chemicals | 15 (2) | 51 (1.9) | 0.83 (0.46 to 1.51) |
*Adjusting for age, sex, residential area, body mass index, education and smoking. Bold values are statistically significant (p<0.05).
†Interaction term with smoking was significant (p<0.05). OR shown assumes most common scenario (never smoker).
EIRA, Epidemiological Investigation of Rheumatoid Arthritis; RA, rheumatoid arthritis; RF, rheumatoid factor.