US-NB* | US-P&F* | NB* | |
Tissue yield and quality15 | = | = | Number of graded ST fragments/total number of ST fragments <Small joints trend p=0.057 <Large joint p=0.048 |
Large joints RNA yield (quantity)15 | A>US-NB: p=0.002 | A>US-P&F: p=0.00REF | – |
Large joints RNA quality (RIN)15 | A>US-NB: p=0.0018 | A=US-P&F: p=0.068 | – |
Small and large joints Immune cell infiltrate and pathotype15 | = | = | = |
Tolerance VAS pain, swelling, stiffness16 | = | = | – |
Willingness to repeat16 | US-P&F>US-NB: p<0.01 A>US-NB: p<0.01 | = | – |
*Arthroscopy is the reference in this table.
=, no statistical difference; –, not done; A, arthroscopy; NB, needle biopsy; P&F, portal and forceps; RIN, RNA integrity number; ST, synovial tissue; US, ultrasound; VAS, visual analogic scale.