Table 2

Information sources used for the various sections of the decision aid

Sections of prototypeInformation sources
I: Health condition and personal risk factors
  • Landmark gout literature provided by the steering group.

II: The personalised risk on future gout flares without ULT
  • Literature search of Cochrane database did not meet the needs; a review on the relation between sUA and gout flares was used instead.

III: Lifestyle changes and treatment of acute flares
  • SLR on effectiveness and side effect treatment acute gout flares.

  • SLR on effect lifestyle in gout outcomes provided by the steering group.

  • National and international recommendations on gout management.

  • Dutch exercise norm.

IV: Effect of ULT
  • Literature search of Cochrane database did not meet the needs; a review on the relation between sUA and gout flares was used instead.

  • Role of flare prophylaxis added per advice of the steering group.

V: Option grid
  • Literature search on available decision aids provided a list of attributes that informed the NGT meetings.

  • NGT ranked attributes (six highest were included).

  • Cochrane review on comparative effectiveness of ULT on gout flares.

  • National and international recommendations on gout management.

  • For side effects information and data provided by the Dutch Healthcare Institute (www.farmacotherapeutischkompas.nl).

VI: Final treatment decision
  • Example retrieved from literature search for decision aids (to inform NGT) informed the design of this page.

  • NGT, nominal group technique; SLR, systematic literature review; sUA, serum uric acid; ULT, urate-lowering therapy.