Comparison clinical features and outcome measures between JIA patients who had the PhGA scored as 0 or >0 and all other 2011 ID criteria met
| Patients with PhGA=0 (n=1680) | Patients with PhGA>0 (n=536) | P value | |
| Female | 1080 (64) (0.1) | 343 (64) (0) | 0.9 |
| Mean (SD) age at disease onset, years | 5.7 (4.0) (0) | 6.9 (4.3) (0.2) | <0.001 |
| Mean (SD) age at visit, years | 11.0 (4.5) (0) | 11.5 (4.6) (0) | 0.008 |
| Mean (SD) disease duration, years | 5.2 (3.6) (0) | 4.6 (3.6) (0) | <0.001 |
| ILAR category | (0) | (0) | <0.001 |
| Systemic arthritis | 229 (14) | 69 (13) | |
| Oligoarthritis | 805 (48) | 196 (37) | |
| RF-negative polyarthritis | 362 (22) | 121 (23) | |
| RF-positive polyarthritis | 31 (1.8) | 23 (4.3) | |
| Psoriatic arthritis | 43 (2.6) | 27 (5.0) | |
| ERA | 145 (8.6) | 72 (13) | |
| Undifferentiated arthritis | 65 (3.9) | 28 (5.2) | |
| Enthesitis by history | 7 (0.4) (1.1) | 22 (4.1) (0.2) | <0.001 |
| Dactylitis by history | 11 (0.7) (0.8) | 7 (1.3) (0.2) | 0.2 |
| Psoriasis by history | 3 (0.2) (0) | 5 (1.0) (0) | 0.023 |
| Physician-reported outcomes | |||
| Tender joint count >0 | 18 (1.1) (0) | 101 (19) (0) | <0.001 |
| Restricted joint count >0 | 226 (13) (0) | 185 (35) (0) | <0.001 |
| Proximal tender joints count >0 | 3 (0.2) (0) | 33 (6.2) (0) | <0.001 |
| Distal large tender joints count >0 | 16 (1.0) (0) | 75 (14) (0) | <0.001 |
| Distal small tender joints count >0 | 3 (0.2) (0) | 12 (2.2) (0) | <0.001 |
| JADI-articular >0 | 142 (8.5) (0.1) | 96 (18) (0) | <0.001 |
| JADI-extra-articular >0 | 147 (8.8) (0) | 58 (11) (0) | 0.15 |
| Parent-reported outcomes | |||
| Well-being VAS >0 | 453 (27) (0) | 314 (59) (0) | <0.001 |
| Disease activity VAS >0 | 367 (22) (1.7) | 310 (59) (1.5) | <0.001 |
| Pain VAS >0 | 358 (21) (0.4) | 296 (55) (0.4) | <0.001 |
| Physical function score >0 | 385 (23) (0) | 217 (40) (0) | <0.001 |
| Physical health score >0 | 592 (36) (1.0) | 335 (64) (2.1) | <0.001 |
| Psychosocial health score >0 | 680 (41) (1.7) | 292 (56) (2.6) | <0.001 |
| Satisfied with illness outcome | 1565 (94) (0.5) | 433 (82) (1.1) | <0.001 |
| Inactive disease by the JADAS10 | 1467 (87) (0) | 214 (40) (0) | <0.001 |
Data are the number (percentage) unless otherwise indicated. The percentage of missing data is indicated in the latter parentheses.
ERA, Enthesitis-related arthritis; JADAS, Juvenile Arthritis Disease Activity Score; JADI, Juvenile Arthritis Damage Index; JIA, juvenile idiopathic arthritis; PhGA, physician global assessment of overall disease activity; RF, rheumatoid factor; VAS, visual analogue scale.