Patient’s characterisics | | |
Age (years) | | |
Median (IQR) | 44.0 (34.0 ; 59.0) | 29.0 (19.0 ; 43.0) |
<18 | 4/50 (8.0) | 13/67 (19.4) |
18–64 | 37/50 (74.0) | 45/67 (67.2) |
≥65 | 9/50 (18.0) | 9/67 (13.4) |
Female gender | 29/50 (45.3) | 35/67 (54.7) |
Comorbidities | | |
Respiratory disease | 3/50 (6.0) | 3/67 (4.5) |
Interstitial lung disease | 0 | 0 |
COPD | 1/50 (2.0) | 1/67 (1.5) |
Asthma | 2/50 (4.0) | 2/67 (3.0) |
Cardiovascular disease | 6/50 (12.0) | 5/67 (7.5) |
Coronary heart diseases | 4/50 (8.0) | 5/67 (7.5) |
Stroke | 4/50 (8.0) | 1/67 (1.5) |
Diabetes | 5/50 (10.0) | 3/67 (4.5) |
BMI (kg/m²) | 25.0 (21.0 ; 28.0) | 22.0 (20.0 ; 25.5) |
<30 | 38/47 (80.9) | 60/64 (93.8) |
30–39.9 | 6/47 (12.8) | 4/64 (6.3) |
≥40 | 3/47 (6.4) | 0/64 (0.0) |
Hypertension | 6/50 (12.0) | 6/67 (9.0) |
Cancer | 2/50 (4.0) | 1/67 (1.5) |
Smoking | 6/50 (12.0) | 2/67 (3.0) |
Chronic renal failure | 2/50 (4.0) | 3/67 (4.5) |
Number comorbidities, median (IQR) | | |
0 | 25/50 (50.0) | 51/67 (76.1) |
1 | 16/50 (32.0) | 10/67 (14.9) |
2 | 5/50 (10.0) | 3/67 (4.5) |
3 | 3/50 (6.0) | 1/67 (1.5) |
4 | 1/50 (2.0) | 2/67 (3.0) |
>4 | 0 | 0 |
Rheumatic or inflammatory Diseases treatments | |
Corticosteroid | 19/50 (38.0) | 1/67 (1.5) |
Systemic corticosteroid doses≥10 mg | 6/19 (31.6) | 0/1 (0.0) |
NSSAIDs | 1/50 (2.0) | 1/67 (1.5) |
Colchicine | 15/50 (30.0) | 57/67 (85.1) |
Hydroxychloroquine | 0 | 0 |
Methotrexate | 13/50 (26.0) | 0/67 (0.0) |
Leflunomide | 0 | 0 |
Salazopyrine | 0 | 0 |
Mycophenolate Mofetil / mycophenolic acid | 0 | 0 |
Azathioprine | 4/50 (8.0) | 0/67 (0.0) |
IgIV | 0 | 0 |
Targeted biologic or synthetic therapies | | |
anti-TNF | 14/50 (28.0) | 4/67 (6.0) |
anti-IL6 | 5/50 (10.0) | 0/67 (0.0) |
anti-IL17A | 0 | 0 |
anti-IL1 | 4/50 (8.0) | 8/67 (11.9) |
abatacept | 1/50 (2.0) | 0/67 (0.0) |
JAK inhibitor | 1/50 (2.0) | 0/67 (0.0) |
Other biologics | 1/50 (2.0) | 0/67 (0.0) |
Severity of COVID-19 Infection | | |
Mild | 35/50 (70.0) | 55/67 (82.1) |
Moderate | 9/50 (18.0) | 8/67 (11.9) |
Severe | 6/50 (12.0) | 4/67 (6.0) |
Length of hospital stay (days), median (IQR) | 12 (6 to NA) | 5 (2 to NA) |
Death | 4/50 (8.0) | 2/67 (3.0) |