Quality/effect size | None | Small | Medium | Large |
Very low | Artemisia annua (function), bromelain (pain), ginger (pain), green tea extract (pain, function), Mediterranean diet (function), Scutellaria baicalensis and Acacia catechu (6MWT, CRP), Uncaria guianensis extract (pain), WFPB diet (pain), vitamin B12 (pain) | Aquamin (pain), Artemisia annua (pain), bromelain (function), vitamin B3 (pain), vitamin C+E (pain) | Aquamin (function), creatine (pain, function), egg-shell membrane (pain, function, stiffness), multi-mineral (pain, function), promerim (pain), seaweed extract (pain, function), sesame powder (pain), turmeric (pain) | Calcium fructobate (CRP, ESR), L-carnitine (pain, function), passion fruit extract (pain, function), Phellodendron amurense extract (pain) |
Low | Cherry juice (pain, function), Elaeagnus angustifoli extract +Boswellia thurifera (pain, function), garlic (pain, function), pomegranate (pain, function), vitamin C (radiographic progression), vitamin E (pain, function) | Argan oil (pain), Channa striatus (pain), Elaeagnus angustifoli extract (pain, function), fruit powder (pain, function), green lipped mussel extract (pain), low calorie diet (pain, function), methylsulfonylmethane (pain), multi-vitamins (pain), vitamin D (radiographic progression) | Argan oil (function), Boswellia Serrata (pain, function), Channa striatus (function), collagen (pain, function), fibre (pain), fat (JSW), Lactobacillus casei shirota (stiffness), milk (JSW) | Curcuma longa (pain, function), curcumin (pain, function), Lactobacillus casei shirota (pain, function), methylsulfonylmethane (function), pine tree extract (pain, function), Rosa canina mix (pain, function) |
Moderate | Fish oil (pain, function) | ASU (pain, function), chondroitin (pain, function), glucosamine (pain, function), vitamin D (pain, function) | – | – |
High | – | – | – | – |
ASU, avocado and soybean unsaponifiable; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; JSW, joint space width; 6MWT, 6 min walk test; WFPB, whole food plant based.