ESSPRI versus clinical parameters | SjS (n=172) | Sicca (n=145) | ||
Β (95% CI) | P value | Β (95% CI) | P value | |
Age | 0.01 (−0.02 to 0.4) | 0.37 | −0.01 (−0.04 to 0.03) | 0.60 |
HADS A | 0.15 (0.07 to 0.23) | <0.0001 | 0.1 (0.02 to 0.2) | 0.02 |
HADS D | 0.16 (0.07 to 0.26) | 0.001 | 0.24 (0.14 to 0.34) | <0.0001 |
BMI | 0.1 (0.005 to 0.15) | 0.04 | 0.1 (0.06 to 0.18) | <0.0001 |
Schirmer’ s test | −0.03 (−0.07 to 0.13) | 0.17 | 0.02 (−0.01 to 0.05) | 0.24 |
Unstimulated salivary flow | −0.2 (-0.73 to 0.37) | 0.51 | −0.5 (-0.92 to 0.12) | 0.01 |
C3 | 1.8 (0.22 to 3.6) | 0.03 | 2.5 (0.89 to 4) | 0.002 |
C4 | 0.6 (−0.16 to 0.24) | 0.64 | 5.2 (0.72 to 9.78) | 0.02 |
IgG | −0.01 (−0.06 to 0.04) | 0.96 | 0.02 (-0.11 to 0.15) | 0.79 |
K/L free light chain quotient | −0.2 (−0.62 to 0.20) | 0.31 | 0.3 (−0.55 to 1.11) | 0.51 |
CRP | 0.01 (−0.11 to 0.13) | 0.85 | 0.07 (−0.03 to 0.16) | 0.17 |
Values shown are the linear regression unstandardised coefficients and 95% CIs.
P values <0.05 marked in bold.
BMI, body mass index; CRP, C reactive protein; ESSPRI, EULAR Sjögren’s Syndrome Patient-Reported Index; HADS, Hospital Anxiety and Depression Scale; SjS, Sjogren’s syndrome.