Table 1

Descriptive statistics of Hounsfield units (HU) values according to the measurements of readers 1 and 2, inter-reader reliability and agreement for each vertebral level

VertebraReader 1—HU valuesReader 2—HU valuesICC†SDD‡
Mean (SD)RangeMean (SD)Range
C3354 (106)162–643355 (108)158–6470.986
C4350 (113)119–661350 (113)122–6681.005
C5333 (109)83–601333 (109)88–6050.906
C6290 (88)82–481289 (88)83–4791.005
C7271 (83)79–447270 (82)81–4401.007
T1229 (86)69–431224 (87)67–4261.006
T2246 (59)55–382240 (58)57–3840.996
T3230 (71)88–402223 (69)90–4070.996
T4222 (69)41–333210 (66)43–3350.995
T5208 (56)59–369204 (57)53–3620.984
T6205 (63)31–319194 (63)32–3120.985
T7198 (78)−9 to 353187 (74)−10 to 3590.995
T8185 (68)7–299177 (65)3–3060.997
T9194 (72)−15 to 307181 (69)−17 to 3040.996
T10194 (73)18–375181 (71)23–3720.995
T11176 (60)29–305168 (60)30–3020.975
T12177 (62)28–367166 (58)23–3720.976
L1165 (55)11–325162 (54)6–3170.898
L2158 (51)−13 to 258153 (51)−9 to 2530.944
L3154 (65)−37 to 345150 (65)−34 to 3460.898
L4163 (84)−35 to 459156 (82)−37 to 4610.917
L5159 (65)−12 to 292158 (63)−8 to 2860.908
  • *Cervical spine values are based on a total of 44 vertebrae scored at each level (C3–C7) by both readers. The values for thoracic and lumbar spine are based on a total of 50 and 49 vertebrae scored at each level (T1 to L5) by readers 1 and 2, respectively.

  • †Two-way mixed effects method, single measurements, absolute agreement.

  • ‡SDD=1.96 × SDdifference /(√k); SDdifference is the SD of the differences in status scores between two readers; k is the number of readers (n=2).

  • HU, Hounsfield Units; ICC, intraclass correlation coefficients; SDD, smallest detectable difference.