Table 1

Description of patients with elevated PGA and tender joint counts of 0 or 1 vs all BRASS patients at the 11th follow-up examination

TJC/SJC both ≤1 and PGA ≥3
(n=49)*
All BRASS participants excluding study group (n=223)
TJC (median/IQR)0 (0, 1)0 (0, 3)
SJC (median/IQR)0 (0, 1)0 (0, 2)
Patient Global Assessment (0–10) (median/IQR)5 (4, 6)1.5 (1, 5)
CRP in mg/dL (median/IQR)2.6 (1.0, 9.0)1.7 (0.8, 3.9)
DAS28 CRP score (median/IQR)2.03 (1.61, 2.32)2.18 (1.61, 2.97)
% on steroids24.529.3
% on methotrexate4952
% on biologic agent67.464.6
Age in years (median/IQR)65 (53, 73)66 (56, 72)
Sex (% women)85.783.9
BMI (median/IQR)25.7 (22.4, 31.1)27 (23, 30.7)
Smoker (% current/% ever)2.3/59.22.1/38.6
Race (% White)95.995.1
Ethnicity (% non-Hispanic)95.998.2
Disease duration in years (median/IQR)20 (15, 35)21 (15, 31)
Depression diagnosed or treated in past year (%)22.7
  • *Of the 272 subjects at visit 11, 54 actually met the criteria for focus with joint counts 0 or 1 and PGA >3, but of these only 49 had concurrent data on all symptoms. Some data not available in entire cohort.

  • BMI, body mass index; CRP, C reactive protein; DAS28, disease activity score in 28 joints; PGA, patient global assessment; SJC, swollen joint count; TJC, tender joint count.