Recurrence rate of axSpA among siblings and children in three studies
| Relatives of male probands | First-degree relatives | ||
| # AxSpA/total Swiss study | # AxSpA/total Swedish study18 | # AxSpA/total UK study17 | |
| Sibs | 12/90 (13.3%) | 447/12576 (3.6%) | 243/3177 (7.7%) 5 |
| Children | 15/119 (12.6%) 1 | 294/15293 (1.9%) 2 | 48/772 (6.2%) 3 |
| Sons | 5/53 (9.4%) 8 | 194/7817 (2.5%) 4 | 35/396 (8.8%) 6 |
| Daughters | 10/66 (15.2%) 9 | 100/7476 (1.3%) 4,7 | 13/376 (3.5%) 6 |
| Relatives of female probands | |||
| Sibs | 8/46 (17.4%) | 236/6576 (3.6%) | 142/1286 (11.0%) 5 |
| Children | 12/29 (41.4%) 1 | 204/8547 (2.4%) 2 | 40/375 (10.7%) 3 |
| Sons | 4/11 (36.4%) 8 | 104/4358 (2.4%) | 23/185 (12.4%) |
| Daughters | 8/18 (44.4%) 9 | 100/4189 (2.4%) 7 | 17/190 (8.9%) |
| Criteria for probands HLA-B27 status of probands Age of children | New York 100% HLA-B27 +100% all>45 years | New York estimated >50% HLA-B27 unknown non-specified | New York 100% HLA-B27 estimated 92% all >30 years |
The Swiss and UK studies comprise probands of AS patient societies, whereas the Swedish study is based on national registers.
1p=0.00032; 2p=0.0162; 3p=0.00791; 4p=0.00000; 5p=0.00026; 6p=0.00197; 7p=0.00003.
8p=0.0193; 9p=0.00726.
AS, ankylosing spondylitis.