Table 1

Baseline mean and mean change from baseline to week 104 in mSASSS*

UPA 15 mg QDPBO to UPA 15 mg QDTotal
Baseline, mean (SD)7.5 (11.1) n=928.8 (12.1) n=948.1 (11.6) n=186
Change from baseline to week 104   
 Mean (95% CI†)0.6 (0.1 to 1.1) n=690.8 (0.2 to 1.4) n=670.7 (0.3 to 1.1) n=136
 LS mean (95% CI†)0.6 (0.0 to 1.2) n=690.9 (0.3 to 1.5) n=670.7 (0.3 to 1.2) n=136

  • *Data were obtained in a dedicated reading session that included baseline and week 104 images.

  • †95% CIs were calculated based on the t-distribution.

  • LS, least squares; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; PBO, placebo; QD, once daily; UPA, upadacitinib.