New-onset IMID (N=13) | No now onset IMID (N=75) | |||
N | % | N | % | |
Fever | 3 | 23 | 15 | 20 |
Dyspnoea | 4 | 31 | 11 | 15 |
Cough | 0 | 0 | 3 | 4 |
Fatigue | 0 | 0 | 15 | 20 |
Nausea/vomiting | 0 | 0 | 9 | 12 |
Syncope/pre-syncope | 0 | 0 | 7 | 9 |
Chest pain* | 4 | 31 | 1 | 1 |
Abdominal pain/diarrhoea | 3 | 23 | 22 | 29 |
Anorexia/weight loss | 0 | 0 | 4 | 5 |
Melaena | 0 | 0 | 2 | 3 |
Arthralgia | 1 | 8 | 2 | 3 |
Back pain | 0 | 0 | 4 | 5 |
Arthritis | 1 | 8 | 2 | 3 |
Lower limbs deep vein thrombosis | 1 | 8 | 2 | 3 |
Pulmonary fibrosis | 1 | 8 | 0 | 0 |
Purpura | 1 | 8 | 0 | 0 |
Muscle weakness | 1 | 8 | 0 | 0 |
Thrombocytopaenia | 1 | 8 | 1 | 1 |
Dizziness | 0 | 0 | 2 | 3 |
Jaundice | 0 | 0 | 2 | 3 |
Numbness | 0 | 0 | 2 | 3 |
Confused state | 0 | 0 | 4 | 5 |
Ankle oedema | 0 | 0 | 3 | 4 |
Erithematous cutaneous lesions | 0 | 0 | 2 | 3 |
Fall without loss of consciousness | 0 | 0 | 2 | 3 |
Acute kindey insufficiency | 0 | 0 | 2 | 3 |
Other symptoms/signs†| 0 | 0 | 7 | 9 |
*P=0.00086.
†Displayed by only one patient out of the 75 with no new-onset IMID and by no patient out of the 13 subsequently diagnosed with IMID. These symptoms/signs included: macroscopic haematuria, ab-ingestis pneumonitis, burning mouth syndrome, respiratory failure, headache, oliguria, oesophageal varices.