Baseline clinical characteristics of people with systemic autoimmune rheumatic diseases with confirmed COVID-19, overall and stratified by resolved or prolonged symptom duration by US Centers for Disease Control and Prevention definition of 28 days or longer (n=441)
| Overall N=441 | Symptoms resolved in <28 days N=334 | Prolonged symptom duration 28 days or longer (active or resolved) N=107 | |
| SARD type | |||
| Rheumatoid arthritis | 174 (39.5) | 139 (41.6) | 35 (32.7) |
| Systemic lupus erythematosus | 69 (15.6) | 55 (16.5) | 14 (13.1) |
| Myositis | 51 (11.6) | 38 (11.4) | 13 (12.1) |
| Sjögren’s syndrome | 51 (11.6) | 36 (10.8) | 15 (14) |
| Spondyloarthritis, other than psoriatic arthritis | 50 (11.3) | 33 (9.9) | 17 (15.9) |
| Systemic vasculitis | 32 (7.3) | 24 (7.2) | 8 (7.5) |
| Psoriatic arthritis | 31 (7.0) | 26 (7.8) | 5 (4.7) |
| Systemic sclerosis | 18 (4.1) | 16 (4.8) | 2 (1.9) |
| Other connective tissue disease* | 15 (3.4) | 11 (3.3) | 4 (3.7) |
| Antiphospholipid syndrome | 11 (2.5) | 7 (2.1) | 4 (3.7) |
| Autoinflammatory disease | 4 (0.9) | 3 (0.9) | 1 (0.9) |
| Sarcoidosis | 2 (0.5) | 2 (0.6) | 0 (0) |
| Comorbidity count, mean (SD) | 4.5 (2.5) | 4.3 (2.5) | 5.0 (2.4) |
| Individual comorbidities | |||
| Hypertension | 117 (26.5) | 79 (23.7) | 38 (35.5) |
| Obesity | 102 (23.1) | 71 (21.3) | 31 (29.0) |
| Lung disease† | 80 (18.1) | 55 (16.5) | 25 (23.4) |
| Fibromyalgia | 51 (11.6) | 35 (10.5) | 16 (15.0) |
| Osteoarthritis | 35 (7.9) | 21 (6.3) | 14 (13.1) |
| Diabetes | 28 (6.3) | 20 (6.0) | 8 (7.5) |
| Cardiovascular disease | 17 (3.9) | 10 (3.0) | 7 (6.5) |
| No comorbidity | 145 (32.9) | 120 (35.9) | 25 (23.4) |
N (%) are presented.
*Other connective tissue disease includes mixed connective tissue disease and undifferentiated connective tissue disease.
†Lung disease includes asthma, emphysema, chronic bronchitis, chronic obstructive pulmonary disease, pulmonary hypertension, interstitial lung disease, idiopathic pulmonary fibrosis and other lung diseases.
SARD, systemic autoimmune rheumatic disease.