Characteristics of psoriatic arthritis in patients with and without variants in genes associated with autoinflammatory disorders
| Characteristic | At least one variant in an AD-AID/IEI-associated gene (n=20) | No variant an AD-AID/IEI-associated gene (n=100) | OR (95% CI) | P value |
| Psoriasis—n (%) | 16 (80) | 80 (80) | 1 (0.3 to 3.32) | 1 |
| Pustular psoriasis—n (%) | 5 (25) | 9 (9) | 3.37 (0.99 to 11.44) | 0.0419* |
| Nail psoriasis—n (%) | 1 (5) | 8 (8) | 0.6 (0.07 to 5.13) | 0.64 |
| Oligoarthritis—n (%) | 7 (35) | 24 (24) | 1.7 (0.61 to 4.76) | 1 |
| Polyarthritis—n (%) | 9 (45) | 45 (45) | 1 (0.38 to 2.62) | 1 |
| Axial spondyloarthritis—n (%) | 4 (20) | 31 (31) | 0.56 (0.17 to 1.8) | 0.3232 |
| Enthesitis—n (%) | 3 (15) | 32 (32) | 0.4 (0.11 to 1.49) | 0.1620 |
| Anterior uveitis—n (%) | 0 (0) | 6 (6) | 0.36 (0.02 to 6.55) | 0.2611 |
| Inflammatory bowel disease—n (%) | 3 (15) | 2 (2) | 8.65 (1.34 to 59.67) | 0.0079** |
| Dactylitis—n (%) | 1 (5) | 10 (10) | 0.47 (0.06 to 3.93) | 0.4793 |
| Other autoimmune disorder—n (%) | 7 (35) | 29 (29) | 1.32 (0.48 to 3.64) | 0.593 |
| Hashimoto’s thyroiditis | 0 (0) | 8 (8) | 0.27 (0.01 to 4.79) | 0.3494 |
| Giant cell arteritis | 0 (0) | 3 (3) | 0.68 (0.03 to 13.67) | 1 |
*p<0.05; **p<001.
AD, autosomal dominant; AID, autoinflammatory disorder; IEI, inborn error of immunity; n, number; N, total number.