Table 6

Association between RA disease characteristics and sarcopenia

	EWGSOP2				FNIH
	Crude ORs (95% CI)	P value	Adjusted* ORs (95% CI)	P value	Crude ORs (95% CI)	P value	Adjusted* ORs (95% CI)	P value
Sex
Male	ref.		–	–	ref.		–	–
Female	0.56 (0.17 to 1.89)	0.35	–	–	0.42 (0.10 to 1.79)	0.34	–	–
Age (years)	1.03 (0.97 to 1.08)	0.36	–	–	1.10 (1.00 to 1.14)	0.12	–	–
Height (cm)	1.05 (0.99 to 1.13)	0.13	1.08 (0.98 to 1.19)	0.14	0.87 (0.78 to 0.96)	0.006	0.75 (0.64 to 0.88)	0.0003
Weight (kg)	0.95 (0.90 to 0.99)	0.03	0.92 (0.86 to 0.97)	0.006	1.01 (0.96 to 1.01)	0.61	1.01 (0.95 to 1.07)	0.82
BMI (kg/m²)	0.74 (0.62 to 0.90)	0.002	0.70 (0.57 to 0.87)	0.001	1.18 (1.02 to 1.36)	0.03	1.20 (1.02 to 1.41)	0.03
Fat mass (%)	0.99 (0.92 to 1.10)	0.80	1.00 (0.92 to 1.10)	0.92	1.12 (1.01 to 1.25)	0.04	1.21 (1.07 to 1.38)	0.004
DAS28_CRP	1.34 (0.82 to 2.19)	0.25	1.38 (0.85 to 2.24)	0.19	1.56 (0.87 to 2.79)	0.14	1.63 (0.93 to 2.85)	0.09
CRP(mg/L)	1.06 (1.02 to 1.10)	0.008	1.05 (1.01 to 1.10)	0.02	1.10 (1.01 to 1.11)	0.02	1.06 (1.01 to 1.11)	0.03
Disease duration (years)	1.07 (1.02 to 1.12)	0.005	1.08 (1.02 to 1.36)	0.006	1.05 (0.98 to 1.11)	0.17	1.04 (0.97 to 1.11)	0.25
CG current
No	ref.		ref.		ref.		ref.
Yes	5.3 (1.15 to 24.4)	0.03	5.25 (2.14 to 24.18)	0.03	6.6 (0.80 to 54.37)	0.08	6.5 (0.78 to 53.56)	0.08
bDMARDs current
No	ref.		ref.		ref.		ref.
Yes	2.72 (0.82 to 9.0)	0.10	2.80 (0.84 to 9.40)	0.10	3.6 (0.71 to 18.1)	0.12	3.87 (0.75 to 19.95)	0.11
Cumulative dose prednisone equivalent (g)	1.04 (1.02 to 1.05)	<0.0001	1.04 (1.02 to 1.05)	<0.0001	1.02 (1.00 to 1.04)	0.04	1.02 (1.00 to 1.04)	0.05
≥1 × sports/ week
No	ref.		ref.		ref.		ref.
Yes	0.5 (0.16 to 1.54)	0.23	0.51 (0.17 to 1.60)	0.25	0.26 (0.06 to 1.10)	0.07	0.26 (0.06 to 1.13)	0.07
HAQ (score 0–3)	2.20 (1.17 to 4.10)	0.02	2.50 (1.27 to 4.86)	0.008	2.31 (1.10 to 5.04)	0.04	2.77 (1.17 to 6.59)	0.02
ABC-scale (0–100)	0.98 (0.96 to 1.00)	0.11	0.98 (0.96 to 1.00)	0.11	0.97 (0.95 to 1.00)	0.09	0.98 (0.95 to 1.00)	0.10
IPAQ (total METs)	1.00 (1.00 to 1.00)	0.26	1.00 (1.00 to 1.00)	0.27	1.00 (1.00 to 1.00)	0.26	1.00 (1.00 to 1.00)	0.30

Bold values: p<0.05 significant.
*Analyses adjusted for age and sex.
ABC-scale, Activity-specific Balance Confidence Scale; bDMARDS, biological disease-modifying antirheumatic drugs; BMI, body mass index; CG, glucocorticoids current; CRP, C reactive protein; DAS28_CRP, Disease Activity Score of 28 joints including C reactive protein; EWGSOP2, European Working Group on Sarcopenia in Older People; FNIH, Foundation for the National Institutes of Health; HAQ, Health Assessment Questionnaire; IPAQ, International Physical Activity Questionnaire; MET, metabolic equivalent; RA, rheumatoid arthritis.