Table 3

Comparison of sarcopenia parameter in RA and controls

VariableRA n=289Controls n=280P value
ALM (kg), mean±SD19.1±4.021.1±4.0<0.0001
ALM/ht² (kg/m²), mean±SD6.8±1.07.3±1.2<0.0001
ALM/BMI (kg/BMI), mean±SD0.72±0.140.80±0.18<0.0001
Grip strength (kg), mean±SD23.9±9.032.8±9.5<0.0001
Chair rise time (s), mean±SD9.6±3.48.5±6.0<0.0001
Gait speed (m/s), mean±SD1.23±0.21
Sarcopenia EWGSOP2
 Low grip strength, n (%)59 (20.4)6 (2.1)<0.0001
 Prolonged chair rise time, n (%)21 (7.3)10 (3.6)0.05
 Slow gait speed, n (%)13 (4.5)6 (2.1)0.12
 Low muscle mass ALMI/ht², n (%)36 (12.5)20 (7.1)0.03
 Probable sarcopenia*, n (%)71 (24.6)15 (5.4)<0.0001
 Confirmed sarcopenia, n (%)13 (4.5)1 (0.4)0.001
 Severe sarcopenia, n (%)00
Sarcopenia FNIH
 Weakness, n (%)59 (20.4)6 (2.1)<0.0001
 Low muscle mass ALM/BMI, n (%)18 (6)22 (7.9)0.45
 Weakness and low ALM/BMI, n (%)8 (2.8)2 (0.7)0.11
  • p<0.05 significant. Data on gait speed in controls are only available as a dichotomous variable.

  • bold values: significant

  • *Low grip strength and/ or prolonged chair rise time.

  • ALM, appendicular lean mass; BMI, body mass index; EWGSOP2, European Working Group on Sarcopenia in Older People; FNIH, Foundation for the National Institutes of Health; RA, rheumatoid arthritis.