Risk of pre-eclampsia in RA, AxSpA and PSA pregnancies versus control pregnancies
Pregnancies, n | Pre-eclampsia events, n (%) | Crude OR (95% CI) | Adjusted OR (95% CI)* | |
RA | 1739 | 67 (3.9) | 1.27 (0.98 to 1.64) | 1.27 (0.96 to 1.67) |
Controls† | 17 390 | 535 (3.1) | REF | REF |
AxSpA | 819 | 34 (4.2) | 1.29 (0.87 to 1.91) | 1.17 (0.76 to 1.78) |
Controls† | 8190 | 267 (3.3) | REF | REF |
PsA | 489 | 26 (5.3) | 2.07 (1.32 to 3.24) | 1.85 (1.10 to 3.12) |
Controls† | 4890 | 129 (2.6) | REF | REF |
ORs were estimated using logistic regression and generalised estimation-equation method.
*Adjusted for country, maternal age, parity, year of delivery, BMI, smoking and education.
†Matched 1:10 on maternal age, parity and calendar year of delivery.
AxSpA, axial spondyloarthritis; BMI, body mass index; PsA, psoriatic arthritis; RA, rheumatoid arthritis.