ORs for perceived risk of developing RA in FDRs of patients with RA in multivariable analysis
| FDR characteristic | Perceived absolute risk | Perceived comparative risk | Perceived experiential risk | Worry about risk | ||||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Gender | ||||||||
| Male* | – | – | – | – | – | – | – | – |
| Female | – | – | – | – | – | – | 1.98 (1.19 to 3.27) | 0.01 |
| Relationship to index patient | ||||||||
| Sibling* | – | – | – | – | – | – | – | – |
| Child | 2.80 (1.70 to 4.61) | <0.001 | 3.43 (2.04 to 5.78) | <0.001 | 3.89 (2.24 to 6.75) | <0.001 | 2.26 (1.30 to 3.94) | 0.004 |
| Health literacy | – | – | – | – | 1.50 (1.00 to 2.25) | 0.05 | – | – |
| Illness perceptions | ||||||||
| Timeline | – | – | 1.25 (1.05 to 1.48) | 0.01 | 1.17 (0.99 to 1.38) | 0.07 | – | – |
| Treatment control | 0.89 (0.79 to 0.99) | 0.03 | 0.91 (0.81 to 1.01) | 0.06 | 0.87 (0.77 to 0.98) | 0.02 | 0.84 (0.74 to 0.94) | 0.004 |
| Concern | – | – | – | – | – | – | 1.36 (1.13 to 1.63) | 0.001 |
| Emotion | – | – | – | – | – | – | 1.20 (1.02 to 1.40) | 0.03 |
| Health anxiety | 1.04 (1.01 to 1.07) | 0.02 | 1.05 (1.01 to 1.07) | 0.01 | 1.07 (1.03 to 1.11) | 0.001 | 1.06 (1.02 to 1.09) | 0.003 |
*Reference group.
FDR, first-degree relative; RA, rheumatoid arthritis.