Clinical description of arthritis
| Paient ID | Sex | Age (years) | Age (years) at diagnosis of PID | Age at diagnosis of arthritis | PAD disorder | Arthritis pattern | Extra-articular disease/enteropathy | Arthritis course | Arthritis classification | Actual arthritis treatment |
| 1 | M | 60 | 30 | 36 | CVID | Polyarthritis (MCP joints, wrists, knees and ankles) | Chronic and non-erosive | perSpA | NSAID | |
| 2 | M | 49 | 20 | 20 | CVID | Oligoarthritis (wrists and knee) | Chronic, in remission, since the age of 30 years and manifesting after a giardiasis | ReA | NSAID | |
| 3 | F | 57 | 35 | 45 | CVID | Polyarthritis (MCP and PIP joints, wrists, elbows and knees) | Enthesitis and Crohn’s disease | Chronic and non-erosive | perSpA | Prednisolone |
| 4 | F | 62 | 46 | 47 | CVID | Polyarthritis (DIP and MCP joints, elbows and shoulders), sacroiliitis and syndesmophytes of the lumbar spine | Anterior uveitis | Chronic and non-erosive | r-axSpA | NSAID |
| 5 | F | 70 | 46 | 58 | CVID | Polyarthritis (DIP and MCP joints, knee and ankle) | Dactylitis and plaque psoriasis | Chronic and non-erosive | PsA | MTX |
| 6 | F | 51 | 4 | 6 | CVID | Polyarthritis (wrists, hips, knees and ankles) | Chronic, erosive and in remission since the age of 19 years | Polyarticular JIA | None | |
| 7 | F | 56 | 41 | 52 | CVID | Oligoarthritis (MCP and DIP joints and ancle) and multiple tendinitis | NLH, coeliac diseasC | Chronic and non-erosive | Undifferentiated arthritis | LFN |
| 8 | M | 71 | 62 | 57 | CVID | Oligoarthritis (ancles) | Recurrent aphthous stomatitis | Chronic and non-erosive | perSpA | NSAID |
| 9 | F | 31 | 21 | 23 | CVID | Oligoarthritis (MCP joints) | NLH | Chronic and non-erosive | Undifferentiated arthritis | NSAID |
| 10 | F | 52 | 37 | 27 | CVID | Polyarthritis (MCP and PIP joints, knee, ankles and MTP joints | Chronic and non-erosive | perSpA | NSAID | |
| 11 | M | 55 | 29 | 38 | CVID | Oligoarthritis (wrists and elbow) | Undifferentiated colitis | Chronic and non-erosive | Undifferentiated arthritis | HCQ |
| 12 | M | 31 | 22 | 25 | CVID | Oligoarthritis (knees) | Plaque psoriasis, nail psoriasis and multiple bursitis | Chronic and erosive | PsA | MTX |
| 13 | F | 38 | 35 | 34 | CVID | Oligoarthritis (wrist and knees) and sacroiliitis | Chronic and non-erosive | nr-axSpA | NSAID | |
| 14 | F | 33 | 17 | 17 | CVID | Symmetrical polyarthritis (MCP and PIP joints and shoulders) | Undifferentiated colitis | Chronic and non-erosive | perSpA | none |
| 15 | F | 56 | 54 | 40 | IgG subclass deficiency | Symmetrical polyarthritis (PIP and MCP joints, shoulders and knees) | Undifferentiated colitis and Raynaud’s phenomenon | Chronic and non-erosive | perSpA | RTX |
| 16 | M | 71 | 50 | 69 | Unclassified antibody deficiency | Symmetrical polyarthritis (PIP and MCP joints, wrists and elbows) | Chronic and erosive | Seronegative RA | Baricitinib | |
| 17 | M | 50 | 50 | 50 | CVID | Oligoarthritis (shoulder and knee) | Raynaud’s phenomenon | Chronic, non-erosive and in remission since the age of 52 | perSpA | None |
| 18 | F | 34 | 33 | 34 | CVID | Polyarthritis (PIP and MCP joints, hip knees and ankles) | Chronic and non-erosive | perSpA | None | |
| 19 | M | 62 | 55 | 56 | CVID | Oligoarthritis (PIP joints) | Enthesitis and undifferentiated colitis | Chronic and non-erosive | perSpA | HCQ |
| 20 | F | 55 | 22 | 22 | CVID | Symmetrical polyarthritis (MCP and PIP joints, elbows and ankles) | Chronica and non-erosive | Seronegative RA | MTX | |
| 21 | F | 36 | 20 | 26 | Unclassified antibody deficiency | Oligoarthritis (wrists and ancles) | Sicca symptoms and Crohn’s disease | Chronic and non-erosive | perSpA | RTX |
| 22 | F | 49 | 38 | 41 | CVID | Polyarthritis (wrists, knees and ankles) | NLH and undifferentiated colitis | Chronic and non-erosive | perSpA | Abatacept |
| 23 | F | 63 | 30 | 54 | CVID | Oligoarthritis (MCP joints) and sacroiliitis | Chronic and non-erosive | nr-axSpA | Prednisolone | |
| 24 | F | 73 | 47 | 34 | CVID | Polyarthritis (wrists, elbows and knees) | Bursitis suprapatellaris and Coeliac disease | Chronic and non-erosive | perSpA | SSZ |
| 25 | F | 85 | 59 | 66 | CVID | Polyarthritis (DIP and PIP joints, wrists and shoulder) | Livedo reticularis, NLC | Chronic and non-erosive | Undifferentiated arthritis | RTX |
| 26 | F | 33 | 25 | 7 | CVID | Polyarthritis (wrists, hips, knees, ancles) | Undifferentiated colitis | Chronic and in remission since the age of 12 years | Polyarticular JIA | None |
| 27 | F | 65 | 34 | 34 | CVID | Oligoarthritis (wrists, knee) and sacroiliitis | Chronic and non-erosive | nr-axSpA | HCQ+NSAR | |
| 28 | M | 40 | 13 | 6 | CID | Symmetrical polyarthritis (PIP and MCP joints and knees) | Recurrent enthesitis | Chronic and non-erosive | Polyarticular JIA | RTX |
| 29 | F | 69 | 66 | 53 | CVID | Symmetrical polyarthritis (PIP, MCP and MTP joints and elbow) | Chronic and erosive | Seronegative RA | Abatacept | |
| 30 | M | 24 | 6 | 21 | CVID | Oligoarthritis (MCP joint, knee and ancles) | Recurrent enthesitis and Crohn’s disease | Chronic and erosive | perSpA | Infliximab |
| 31 | F | 28 | 18 | 16 | CVID | Polyarthritis (MCP joints, wrists and knees), sacroiliitis and spondylitis | Dactylitis, NLH | Chronic and erosive | r-axSpA | Secukinumab |
| 32 | F | 57 | 44 | 47 | SPAD | Sacroiliitis | Chronic and erosive | nr-axSpA | NSAID | |
| 33 | F | 36 | 30 | 30 | CVID | Oligoarthritis (elbow and knee) | Recurrent bursitis and enthesitis and Crohn’s disease | Chronic and non-erosive | perSpA | HCQ |
| 34 | M | 38 | 10 | 11 | CVID | Polyarthritis (MCP joints, wrists and knees) | NLH | Chronic, non-erosive and in remission since the age of 15 | Polyarticular JIA | None |
| 35 | F | 45 | 34 | 17 | CVID | Polyarthritis (MCP, wrists, shoulder and knees) and sacroiliitis | Crohn’s disease | Chronic and non-erosive | nr-axSpa | Infliximab |
| 36 | M | 29 | 4 | 17 | Unclassified antibody deficiency | Oligoarthritis (knees) | Self-limiting and non-erosive | Undifferentiated arthritis | None | |
| 37 | F | 32 | 23 | 29 | CVID | Oligoarthritis (knees) | Chronic and non-erosive | ReA | Prednisolone | |
| 38 | M | 68 | 32 | 33 | CVID | Oligoarthritis (wrist and knees) | Plaque psoriasis | Chronic and non-erosive | PsA | None |
| 39 | M | 32 | 30 | 29 | CVID | Polyarthritis (MCP and PIP joints, wrists and ankles) and developing after traveller’s diarrhoea | Chronic and non-erosive | ReA | None | |
| 40 | F | 26 | 21 | 24 | CVID | Oligoarthritis (DIP and PIP joints) | sicca symptoms, dactylitis | chronic, non-erosive | perSpA | SSZ |
| 41 | F | 55 | 20 | 40 | CVID | Oligoarthritis (wrists), sacroiliitis, spondylitis and syndesmophytes of the lumbar spine | Raynaud’s phenomenon | Chronic anderosive | r-axSpA | Golimumab |
| 42 | F | 65 | 64 | 33 | IgG subclass deficiency | Oligoarthritis (PIP and elbows) | Recurrent enthesitis | Cronic and non-erosive | perSpA | None |
| 43 | F | 47 | 26 | 15 | CVID | Polyarthritis (wrists, knees and ancles) | Plaque, psoriasis and NLH | Chronic and non-erosive | PsA | Prednisolone |
| 44 | F | 24 | 23 | 9 | CVID | Oligoarthritis (knees and temporomandibular joint) | Crohn’s disease | Chronic and non-erosive | Oligoarticular JIA | MTX+adalimumab |
CID, combined immunodeficiency; CVID, common variable immunodeficiency; DIP, distal interphalangeal; F, female; HCQ, hydroxychloroquine; JIA, juvenile idiopathic arthritis; LFN, leflunomide; M, male; MCP, metacarpophalangeal; MTP, metatarsophalangeal; MTX, methotrexate; NLH, nodular lymphoid hyperplasia; nr-axSpA, non-radiographic axial spondyloarthritis; NSAID, non-steroidal anti-inflammatory drug; PAD, primary antibody deficiency; perSpA, peripheral spondyloarthritis; PID, primary immunodeficiency disorder; PIP, proximal interphalangeal; PsA, psoriatic arthritis; RA, rheumatoid arthritis; r-axSpA, radiographic axial spondyloarthritis; ReA, reactive arthritis; RTX, rituximab; SPAD, specific polysaccharide antibody deficiency; SSZ, sulfasalazine.