Patients included (n) | Joints included (n) | β (95% CI) | |
Arm 1: sequential monotherapy | 116 | 3864 | 0.20 (0.18 to 0.23) |
Arm 2: step-up combination therapy starting with methotrexate | 112 | 3773 | 0.12 (0.10 to 0.14) |
Arm 3: initial combination therapy with methotrexate, sulfasalazine and prednisone | 122 | 4052 | 0.14 (0.12 to 0.16) |
Arm 4: initial combination therapy with methotrexate and infliximab | 123 | 4157 | 0.09 (0.08 to 0.11) |