2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | |
>18 years, in million | 8.1 | 7.0 | 7.1 | 7.1 | 7.1 | 7.3 | 7.4 | 7.5 | 7.4 | 7.3 | 7.3 | 7.2 | 7.1 | 7.1 |
RA diagnosis, in 1000 | 98 | 93 | 96 | 102 | 103 | 106 | 112 | 117 | 120 | 138 | 141 | 143 | 144 | 143 |
RA+DMARD, in 1000 | 41 | 41 | 44 | 48 | 52 | 55 | 59 | 63 | 66 | 68 | 78 | 81 | 83 | 85 |
Prevalent ILD | 257 | 632 | 840 | 1033 | 1130 | 1186 | 1285 | 1351 | 1406 | 1463 | 1553 | 1548 | 1541 | 1484 |
Incident ILD | 18 | 63 | 82 | 88 | 94 | 70 | 125 | 120 | 114 | 125 | 157 | 141 | 145 | 90 |
Required for inclusion: RA: 1 inpatient or ≥2 outpatient ICD-10 codes M05, M06 in the respective year AND a prescription of a DMARD (ever). Prevalent ILD in RA: 1 inpatient or ≥2 outpatient ICD-10 codes of J84.1, 8, 9; M05.1+J99.0 in the respective year+≥1 lung diagnostic procedure code (ever). Incident ILD in RA: no ILD diagnosis in all years prior to the index year.
DMARD, disease-modifying antirheumatic drug; ICD-10, International Statistical Classification of Diseases; ILD, interstitial lung disease; RA, rheumatoid arthritis.