Table 3

The demographical and clinical features between IgG4-RD patients with positive and negative AID family history.

ParamentsAID-positive group (n=93)AID-negative group (n=535)P value
Age (years)50.4±14.854.2±12.60.014*
Male/female1.02:11.60:10.061
Disease duration (months)18.0 (4.8, 36)12.0 (5.0, 36)0.382
History of allergy, n (%)49 (92, 53.3)296 (533, 55.5)0.771
Combine with other AID, n (%)15 (16.1)33 (6.2)0.0238*
IgG4-RD RI6 (4, 10)6 (4, 10)0.343
Riedel thyroiditis, n (%)10 (92, 10.9)13 (532, 2.4)0.001*
Numbers of organs involvement3 (2, 4)3 (2, 4)0.613
Cigarette smoking, n (%)29 (69, 42.0)192 (389, 49.4)0.321
Continuous alcohol intake, n (%)3 (68, 4.4)19 (377, 5.0)1
  • *P<0.05

  • AID, autoimmune disease ; IgG4-RD, IgG4-related disease ; IgG4-RD RI, IgG4-RD responder index.