The percent area of vascularity from various ultrasound techniques (mean±SD; unit: %) and their diagnostic performance in detecting the RP-SSc patients with history of digital ulcers
| Ultrasound techniques | RP-SSc patients with history of digital ulcers (n=10) | RP-SSc patients without history of digital ulcers (n=8) | T-test p value | Area under the ROC | Specificity (%) | Sensitivity (%) |
| CDI dorsal | 5.3±5.8 | 9.6±9.1 | 0.27 | 0.59 | 50 | 80 |
| CDI ventral (25 mm2) | 4.6±5.5 | 14.6±11.6 | 0.04 | 0.76 | 50 | 100 |
| CDI ventral (100 mm2) | 2.5±2.7 | 9.0±6.6 | 0.02 | 0.76 | 50 | 100 |
| PDI dorsal | 2.2±2.9 | 4.4±3.7 | 0.19 | 0.65 | 62.5 | 90 |
| PDI ventral (25 mm2) | 2.9±3.8 | 10.1±9.2 | 0.05 | 0.75 | 62.5 | 80 |
| PDI ventral (100 mm2) | 1.6±2.1 | 6.3±5.4 | 0.03 | 0.76 | 62.5 | 90 |
| cSMI dorsal | 10.2±7.0 | 11.0±10.4 | 0.85 | 0.45 | 37.5 | 90 |
| cSMI ventral (25 mm2) | 10.1±5.7 | 16.5±10.0 | 0.12 | 0.74 | 50 | 100 |
| cSMI ventral (100 mm2) | 4.2±3.2 | 8.9±5.5 | 0.05 | 0.76 | 50 | 100 |
| mSMI dorsal | 7.5±2.4 | 8.0±3.0 | 0.73 | 0.48 | 25 | 100 |
| mSMI ventral (25 mm2) | 6.3±3.0 | 8.9±3.5 | 0.13 | 0.71 | 50 | 90 |
| mSMI ventral (100 mm2) | 2.7±1.5 | 5.0±2.4 | 0.04 | 0.75 | 75 | 80 |
CDI, colour Doppler imaging; cSMI, colour-coded superb microvascular imaging; mSMI, monochrome superb microvascular imaging; PDI, power Doppler imaging; ROC, receiver operating characteristic ; RP, Raynaud’s phenomenon; SSc, systemic sclerosis.