Table 3

Univariate and multivariate Cox proportional hazard regression analysis of sustained and point clinical remission in postmenopausal women with baseline SDAI of >11 (N=1446)

	Point remission				Sustained remission
	Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
Variable	HR (95% CIs)	P value	HR (95% CIs)	P value	HR (95% CIs)	P value	HR (95% CIs)	P value
Early menopause	0.806 (0.544 to 1.194)	0.282	–	–	0.988 (0.517 to 1.890)	0.972	–	–
Age	0.992 (0.974 to 1.009)	0.336	–	–	1.007 (0.976 to 1.038)	0.670	–	–
RA duration	0.966 (0.945 to 0.987)	0.002	0.969 (0.948 to 0.990)	0.004	0.913 (0.871 to 0.958)	<0.001	0.921 (0.878 to 0.965)	<0.001
Level of education*	1.303 (0.983 to 1.726)	0.066	–	–	0.886 (0.530 to 1.481)	0.643	–	–
Economic status†	2.020 (1.529 to 2.670)	<0.001	1.677 (1.237 to 2.274)	<0.001	1.809 (1.109 to 2.951)	0.018	1.600 (0.938 to 2.729)	0.084
Baseline pain VAS	0.987 (0.982 to 0.992)	<0.001	0.997 (0.990 to 1.004)	0.456	0.983 (0.974 to 0.992)	<0.001	1.001 (0.989 to 1.013)	0.859
Baseline fatigue VAS	0.988 (0.984 to 0.993)	<0.001	0.993 (0.987 to 0.999)	0.03	0.978 (0.969 to 0.986)	<0.001	0.983 (0.972 to 0.994)	0.003
Baseline sleep disturbance VAS	0.991 (0.986 to 0.995)	<0.001	0.996 (0.990 to 1.002)	0.224	0.986 (0.977 to 0.995)	0.002	0.994 (0.983 to 1.006)	0.313
Baseline SDAI score	0.946 (0.925 to 0.968)	<0.001	0.968 (0.944 to 0.993)	0.011	0.945 (0.906 to 0.986)	0.008	0.981 (0.938 to 1.025)	0.387
Seropositivity	1.211 (0.595 to 2.464)	0.598	–	–	1.023 (0.319 to 3.279)	0.970	–	–

*The reference group received middle school education or less.
†The reference group had a monthly income of <US$1700.
RA, rheumatoid arthritis; SDAI, Simplified Disease Activity Index; VAS, Visual Analogue Scale.